JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB115169

Anti-COMMD4 antibody

Be the first to review this product! Submit a review

|

(5 Publications)

Rabbit Polyclonal COMMD4 antibody. Suitable for WB and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Synthetic Peptide within Human COMMD4 aa 100-200.

View Alternative Names

COMM domain-containing protein 4, COMMD4

1 Images
Western blot - Anti-COMMD4 antibody (AB115169)
  • WB

Unknown

Western blot - Anti-COMMD4 antibody (AB115169)

All lanes:

Western blot - Anti-COMMD4 antibody (ab115169) at 0.4 µg/mL

Lane 1:

HeLa cell lysate at 50 µg

Lane 2:

HeLa cell lysate at 15 µg

Lane 3:

HeLa cell lysate at 5 µg

Lane 4:

293T cell lysate at 50 µg

Predicted band size: 22 kDa

false

Exposure time: 10s

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Synthetic Peptide within Human COMMD4 aa 100-200. The exact immunogen used to generate this antibody is proprietary information.

Q9H0A8

style
left-column

Complementary Products

Primary Antibodies

AB195045

Anti-PAX6 antibody [EPR15858]

BOND RX™ Validated|RabMAb|Recombinant|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PAX6 antibody [EPR15858] (AB195045)

  • 5
  • 9
Primary Antibodies

AB97889

Anti-C16orf62 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C16orf62 antibody (AB97889)

  • 4
  • 1
Primary Antibodies

AB96091

Anti-COMMD7 antibody

Western blot - Anti-COMMD7 antibody (AB96091)

  • 0
  • 0
Primary Antibodies

AB157220

Anti-VPS35 antibody [EPR11501(B)]

KO Validated|RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-VPS35 antibody [EPR11501(B)] (AB157220)

  • 2
  • 1
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000 - 1/10000", "WB-species-notes": "<p></p>" }, "Bat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Chimpanzee": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Elephant": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Gorilla": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Horse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Orangutan": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rhesus monkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: 99% Tris citrate/phosphate
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex (PubMed : 37172566, PubMed : 38459129). May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed : 21778237). Down-regulates activation of NF-kappa-B (PubMed : 23637203).
See full target information COMMD4
style
left-column

Publications (5)

Recent publications for all applications. Explore the full list and refine your search

British journal of cancer 129:2014-2024 PubMed37914802

2023

Targeting the COMMD4-H2B protein complex in lung cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Ming Tang,Joshua T Burgess,Mark Fisher,Didier Boucher,Emma Bolderson,Neha S Gandhi,Kenneth J O'Byrne,Derek J Richard,Amila Suraweera

Cell 186:2219-2237.e29 PubMed37172566

2023

Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.

Applications

Unspecified application

Species

Unspecified reactive species

Michael D Healy,Kerrie E McNally,Rebeka Butkovič,Molly Chilton,Kohji Kato,Joanna Sacharz,Calum McConville,Edmund R R Moody,Shrestha Shaw,Vicente J Planelles-Herrero,Sathish K N Yadav,Jennifer Ross,Ufuk Borucu,Catherine S Palmer,Kai-En Chen,Tristan I Croll,Ryan J Hall,Nikeisha J Caruana,Rajesh Ghai,Thi H D Nguyen,Kate J Heesom,Shinji Saitoh,Imre Berger,Christiane Schaffitzel,Tom A Williams,David A Stroud,Emmanuel Derivery,Brett M Collins,Peter J Cullen

Communications biology 4:484 PubMed33875784

2021

COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks.

Applications

Unspecified application

Species

Unspecified reactive species

Amila Suraweera,Neha S Gandhi,Sam Beard,Joshua T Burgess,Laura V Croft,Emma Bolderson,Ali Naqi,Nicholas W Ashton,Mark N Adams,Kienan I Savage,Shu-Dong Zhang,Kenneth J O'Byrne,Derek J Richard

British journal of cancer 123:591-603 PubMed32439936

2020

Defining COMMD4 as an anti-cancer therapeutic target and prognostic factor in non-small cell lung cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Amila Suraweera,Alex Duff,Mark N Adams,Christian Jekimovs,Pascal H G Duijf,Cheng Liu,Matthew McTaggart,Sam Beard,Kenneth J O' Byrne,Derek J Richard

Physiological reports 7:e14100 PubMed31090216

2019

Signaling responses to high and moderate load strength exercise in trained muscle.

Applications

Unspecified application

Species

Unspecified reactive species

Evgeny A Lysenko,Daniil V Popov,Tatiana F Vepkhvadze,Anna P Sharova,Olga L Vinogradova
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com