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AB110245

Anti-Complex I subunit 8 kDa antibody [17C8E4E11]

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(15 Publications)

Mouse Monoclonal NDUFS8 antibody. Suitable for WB and reacts with Rat, Cow, Mouse, Human samples. Cited in 15 publications.
1 Images
Western blot - Anti-Complex I subunit 8 kDa antibody [17C8E4E11] (AB110245)
  • WB

Unknown

Western blot - Anti-Complex I subunit 8 kDa antibody [17C8E4E11] (AB110245)

All lanes:

Western blot - Anti-Complex I subunit 8 kDa antibody [17C8E4E11] (ab110245) at 1 µg/mL

Lane 1:

Human heart mitochondria at 10 µg

Lane 2:

Bovine heart mitochondria at 4 µg

Lane 3:

Rat heart mitochondria at 10 µg

Lane 4:

Mouse heart mitochondria at 10 µg

Predicted band size: 24 kDa

false

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

17C8E4E11

Isotype

IgG1

Light chain type

kappa

Carrier free

No

Reacts with

Mouse, Rat, Cow, Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Primary Antibodies

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Anti-NDUFB8 antibody [20E9DH10C12]

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Primary Antibodies

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>" }, "Cow": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>" } } }
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Product details

Want a custom formulation?
This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com
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Properties and storage information

Form
Liquid
Purification notes
ab110245 was produced in vitro using hybridomas grown in serum-free medium, and then purified by biochemical fractionation.
Storage buffer
pH: 7.5 Preservative: 0.02% Sodium azide Constituents: HEPES buffered saline
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Do Not Freeze
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information Complex I subunit 8 kDa
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Publications (15)

Recent publications for all applications. Explore the full list and refine your search

Current research in pharmacology and drug discovery 3:100087 PubMed35146419

2022

GSK2606414 attenuates PERK/p-eIF2α/ATF4/CHOP axis and augments mitochondrial function to mitigate high glucose induced neurotoxicity in N2A cells.

Applications

Unspecified application

Species

Unspecified reactive species

Chayanika Gundu,Vijay Kumar Arruri,Bhoomika Sherkhane,Dharmendra Kumar Khatri,Shashi Bala Singh

Journal of inflammation (London, England) 18:31 PubMed34930287

2021

Ginsenoside Rg3 alleviates septic liver injury by regulating the lncRNA TUG1/miR-200c-3p/SIRT1 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Pan Wu,Xiao Yu,Yue Peng,Qian-Lu Wang,Long-Tian Deng,Wei Xing

Vascular pharmacology 142:106946 PubMed34838735

2021

Mitochondrial DNA and TLR9 activation contribute to SARS-CoV-2-induced endothelial cell damage.

Applications

Unspecified application

Species

Unspecified reactive species

Tiago J Costa,Simone R Potje,Thais F C Fraga-Silva,Júlio A da Silva-Neto,Paula R Barros,Daniel Rodrigues,Mirele R Machado,Ronaldo B Martins,Rosangela A Santos-Eichler,Maira N Benatti,Keyla S G de Sá,Carlos Eduardo L Almado,Ítalo A Castro,Marjorie C Pontelli,Leonardo La Serra,Fernando S Carneiro,Christiane Becari,Paulo Louzada-Junior,Rene D R Oliveira,Dario S Zamboni,Eurico Arruda,Maria Auxiliadora-Martins,Fernanda R C Giachini,Vânia L D Bonato,Natasha E Zachara,Gisele F Bomfim,Rita C Tostes

Scientific reports 11:14001 PubMed34234233

2021

The UL16 protein of HSV-1 promotes the metabolism of cell mitochondria by binding to ANT2 protein.

Applications

Unspecified application

Species

Unspecified reactive species

Shiyu Li,Shuting Liu,Zhenning Dai,Qian Zhang,Yichao Xu,Youyu Chen,Zhenyou Jiang,Wenhua Huang,Hanxiao Sun

The Biochemical journal 476:2463-2486 PubMed31431479

2019

Mitofusins modulate the increase in mitochondrial length, bioenergetics and secretory phenotype in therapy-induced senescent melanoma cells.

Applications

Unspecified application

Species

Unspecified reactive species

Jennyfer Martínez,Doménica Tarallo,Laura Martínez-Palma,Sabina Victoria,Mariana Bresque,Sebastián Rodríguez-Bottero,Inés Marmisolle,Carlos Escande,Patricia Cassina,Gabriela Casanova,Mariela Bollati-Fogolín,Caroline Agorio,María Moreno,Celia Quijano

Journal of cellular physiology 231:1364-74 PubMed26530043

2015

Complex-I Alteration and Enhanced Mitochondrial Fusion Are Associated With Prostate Cancer Progression.

Applications

Unspecified application

Species

Unspecified reactive species

Julie V Philley,Anbarasu Kannan,Wenyi Qin,Edward R Sauter,Mitsuo Ikebe,Kate L Hertweck,Dean A Troyer,Oliver J Semmes,Santanu Dasgupta

PloS one 9:e94646 PubMed24722488

2014

Post-translational decrease in respiratory chain proteins in the Polg mutator mouse brain.

Applications

WB

Species

Mouse

David N Hauser,Allissa A Dillman,Jinhui Ding,Yan Li,Mark R Cookson

Mitochondrion 11:108-18 PubMed20727424

2010

Recombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin.

Applications

Unspecified application

Species

Unspecified reactive species

Ravindar R Thomas,Shaharyar M Khan,Francisco R Portell,Rafal M Smigrodzki,James P Bennett

Human gene therapy 20:897-907 PubMed19374590

2009

Mitochondrial gene therapy augments mitochondrial physiology in a Parkinson's disease cell model.

Applications

Unspecified application

Species

Unspecified reactive species

Paula M Keeney,Caitlin K Quigley,Lisa D Dunham,Christina M Papageorge,Shilpa Iyer,Ravindar R Thomas,Kathleen M Schwarz,Patricia A Trimmer,Shaharyar M Khan,Francisco R Portell,Kristen E Bergquist,James P Bennett

Mitochondrion 9:196-203 PubMed19460293

2009

Recombinant mitochondrial transcription factor A with N-terminal mitochondrial transduction domain increases respiration and mitochondrial gene expression.

Applications

WB

Species

Unspecified reactive species

Shilpa Iyer,Ravindar R Thomas,Francisco R Portell,Lisa D Dunham,Caitlin K Quigley,James P Bennett
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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