Anti-Connexin 45/GJA7/Cx45 antibody
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(15 Publications)
Rabbit Polyclonal Connexin 45/GJA7/Cx45 antibody. Suitable for IHC-P, WB and reacts with Human, Rat samples. Cited in 15 publications. Immunogen corresponding to Synthetic Peptide within Human GJC1.
View Alternative Names
GJA7, GJC1, Gap junction gamma-1 protein, Connexin-45, Gap junction alpha-7 protein, Cx45
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Connexin 45/GJA7/Cx45 antibody (AB135474)
Immunohistochemical analysis of paraffin embedded Human brain tissue labelling Connexin 45/GJA7/Cx45 with ab135474 at 1/50 dilution.
- WB
Unknown
Western blot - Anti-Connexin 45/GJA7/Cx45 antibody (AB135474)
All lanes:
Western blot - Anti-Connexin 45/GJA7/Cx45 antibody (ab135474) at 1/500 dilution
All lanes:
Rat heart extracts at 30 µg
Predicted band size: 45 kDa
false
Reactivity data
Properties and storage information
Form
Purification technique
Storage buffer
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Cx45 plays an integral role in intercellular communication by participating in the formation of gap junction channels. It functions as part of the connexin family forming homomeric and heteromeric hemichannels that dock with hemichannels on adjacent cells. This connection is essential for electronic coupling and synchronous activity especially in the cardiac and neural tissues where timely communication is necessary for function.
Pathways
Cx45 contributes significantly to the cardiac conduction system and neural transmission pathways. In cardiac tissues it coordinates with connexin 43 to control electrical signal propagation and regulate heartbeat. Cx45 participates in neural pathways by forming functional networks that support synaptic transmission and neuronal synchronization thereby interacting with proteins like connexin 36.
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Target data
Publications (15)
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Biomolecules 14: PubMed39334940
2024
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iScience 27:109219 PubMed38469561
2024
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Frontiers in cellular neuroscience 17:1240916 PubMed37829672
2023
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Genes 14: PubMed36833374
2023
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Life (Basel, Switzerland) 12: PubMed36013400
2022
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International journal of molecular sciences 23: PubMed35682927
2022
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International journal of molecular sciences 23: PubMed35682601
2022
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Biomedicines 10: PubMed35327391
2022
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International journal of molecular sciences 22: PubMed34639052
2021
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International journal of molecular sciences 22: PubMed33525532
2021
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Product promise
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