Anti-COPRS/COPR5 antibody

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

COPRS contributes to the repression of gene transcription by assisting in the recruitment of histone-modifying complexes. It acts as a scaffold for the assembly of these complexes which leads to the alteration of chromatin structure and suppression of transcriptional activity. COPRS works in association with several corepressor proteins facilitating the formation of larger repressor complexes that are important for maintaining tight control over gene expression.

Pathways

COPRS plays a role in the regulation of gene expression pathways including the histone deacetylation pathway. This protein interacts with histone deacetylases (HDACs) to regulate chromatin structure and gene silencing. COPRS is also linked with the pathway involving the regulation of cell cycle genes collaborating with proteins such as Rb1 to control progression through the cell cycle.