AB15719

Anti-Coronin-1C antibody

Name: Anti-Coronin-1C antibody (ab15719) | Abcam
Brand: Abcam Limited
SKU: AB15719
Price: 535 USD
Availability: InStock
Rating: 4 (1 reviews)

(1 Review)

(3 Publications)

Goat Polyclonal Coronin-1C antibody. Suitable for WB and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Synthetic Peptide within Human CORO1C aa 450 to C-terminus.

View Alternative Names

CRN2, CRNN4, CORO1C, Coronin-1C, Coronin-3, hCRNN4

2 Images

Unknown

Western blot - Anti-Coronin-1C antibody (AB15719)

ab15719 at 0.2μg/ml staining Coronin-1C in human lung lysate by Western blot (ECL)

All lanes:

Western blot - Anti-Coronin-1C antibody (ab15719)

Predicted band size: 53 kDa

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AbReview7084****

Western blot - Anti-Coronin-1C antibody (AB15719)

This blot shows significant non-specific background staining. Increasing the length of the blocking step and including a blocking agent in the primary antibody solution may reduce this.

All lanes:

Western blot - Anti-Coronin-1C antibody (ab15719) at 1/1000 dilution

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Mouse 3T3 fibroblast whole cell lysate (25ug)

Secondary

All lanes:

HRP conjugated bovine anti-goat IgG

Predicted band size: 53 kDa

Observed band size: 55 kDa

false

This image is courtesy of an anonymous Abreview

Key facts

Host species

Goat

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

Synthetic Peptide within Human CORO1C aa 450 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q9ULV4

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.2-1 µg/mL", "WB-species-notes": "<p>A 1 hour primary incubation is recommended for this product.</p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Purification notes

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Storage buffer

pH: 7.3 Preservative: 0.02% Sodium azide Constituents: Tris buffered saline, 0.5% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Plays a role in directed cell migration by regulating the activation and subcellular location of RAC1 (PubMed : 25074804, PubMed : 25925950). Increases the presence of activated RAC1 at the leading edge of migrating cells (PubMed : 25074804, PubMed : 25925950). Required for normal organization of the cytoskeleton, including the actin cytoskeleton, microtubules and the vimentin intermediate filaments (By similarity). Plays a role in endoplasmic reticulum-associated endosome fission : localizes to endosome membrane tubules and promotes recruitment of TMCC1, leading to recruitment of the endoplasmic reticulum to endosome tubules for fission (PubMed : 30220460). Endosome membrane fission of early and late endosomes is essential to separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane (PubMed : 30220460). Required for normal cell proliferation, cell migration, and normal formation of lamellipodia (By similarity). Required for normal distribution of mitochondria within cells (By similarity).. Isoform 3. Involved in myogenic differentiation.

See full target information CORO1C

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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Proteomics 15:2602-17 PubMed25781272

2015

Proteomic screening and identification of microRNA-128 targets in glioma cells.

Applications

Unspecified application

Species

Unspecified reactive species

Bin Yang,Shan Wang,Jiawei Zeng,Yu Zhang,Xiangbin Ruan,Wei Han,Bin Yin,Jiangang Yuan,Boqin Qiang,Wantao Ying,Xiaohong Qian,Xiaozhong Peng

Biochemical and biophysical research communications 395:318-23 PubMed20362548

2010

Glucose-induced translocation of coronin 3 regulates the retrograde transport of the secretory membrane in the pancreatic beta-cells.

Applications

ICC/IF

Species

Mouse

Toshihide Kimura,Shigeki Taniguchi,Kazuo Toya,Ichiro Niki

Journal of cell science 121:3092-8 PubMed18768935

2008

The GDP-dependent Rab27a effector coronin 3 controls endocytosis of secretory membrane in insulin-secreting cell lines.

Applications

Unspecified application

Species

Unspecified reactive species

Toshihide Kimura,Yukiko Kaneko,Shogo Yamada,Hisamitsu Ishihara,Takao Senda,Akihiro Iwamatsu,Ichiro Niki

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Coronin-1C antibody

Western blot - Anti-Coronin-1C antibody (AB15719)

Western blot - Anti-Coronin-1C antibody (AB15719)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (3)

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