AB214354

Anti-Coxsackie Adenovirus Receptor/hCAR antibody

Name: Anti-Coxsackie Adenovirus Receptor/hCAR antibody (ab214354) | Abcam
Brand: Abcam Limited
SKU: AB214354
Price: 510 USD
Availability: InStock
Rating: 3 (2 reviews)

(2 Reviews)

(1 Publication)

Rabbit Polyclonal Coxsackie Adenovirus Receptor/hCAR antibody. Suitable for Flow Cyt, WB and reacts with Mouse, Rat samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human CXADR aa 1-100 conjugated to Keyhole Limpet Haemocyanin.

View Alternative Names

CAR, CXADR, Coxsackievirus and adenovirus receptor, hCAR, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, HCVADR

2 Images

Flow Cytometry - Anti-Coxsackie Adenovirus Receptor/hCAR antibody (AB214354)

Flow Cyt

Supplier Data

Flow Cytometry - Anti-Coxsackie Adenovirus Receptor/hCAR antibody (AB214354)

Flow cytometric analysis of mouse brain cells labeling Coxsackie Adenovirus Receptor/hCAR with ab214354 at 1/50 dilution for 40 minutes followed by incubation with Goat Anti-Rabbit IgG FITC conjugated secondary at 1/100 (green) for 40 minutes compared to control cells (blue).

Supplier Data

Western blot - Anti-Coxsackie Adenovirus Receptor/hCAR antibody (AB214354)

12% Gel.

All lanes:

Western blot - Anti-Coxsackie Adenovirus Receptor/hCAR antibody (ab214354) at 1/200 dilution

Lane 1:

Rat heart lysate

Lane 2:

Rat embryo lysate

Secondary

All lanes:

Goat Anti-Rabbit IgG Antibody (H+L), HRP at 1/3000 dilution

Predicted band size: 40 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse, Rat

Applications

WB, Flow Cyt

applications

Immunogen

Synthetic Peptide within Human CXADR aa 1-100 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

P78310

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "predicted", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1/20 - 1/100", "FlowCyt-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "FlowCyt-species-checked": "guaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/100 - 1/1000", "WB-species-notes": "<p></p>" } } }

style

left-column

style

left-column

Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.4 Preservative: 0.02% Proclin 300 Constituents: 50% Glycerol (glycerin, glycerine), 48.98% TBS, 1X, 1% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

style

left-column

style

left-column

style

left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

Target data

Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.. (Microbial infection) Acts as a receptor for adenovirus type C.. (Microbial infection) Acts as a receptor for Coxsackievirus B1 to B6.

See full target information CXADR

style

left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in pharmacology 11:520486 PubMed33101012

2020

Circular RNA Involved in the Protective Effect of L. on Myocardial Ischemic/Re-Perfused Injury.

Applications

Unspecified application

Species

Unspecified reactive species

Yongzhi Xiao,Diafara Boureima Oumarou,Shuang Wang,Yingzhe Liu

View all publications

style

left-column

style

left-column

style

right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Coxsackie Adenovirus Receptor/hCAR antibody

Flow Cytometry - Anti-Coxsackie Adenovirus Receptor/hCAR antibody (AB214354)

Western blot - Anti-Coxsackie Adenovirus Receptor/hCAR antibody (AB214354)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (1)

Alternative Products

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Complementary Products

Assay Kits

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Product promise