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AB155238

Anti-CP2c antibody

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(3 Publications)

Rabbit Polyclonal CP2c antibody. Suitable for WB and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human TFCP2 aa 1-200.

View Alternative Names

LSF, SEF, TFCP2, Alpha-globin transcription factor CP2, SAA3 enhancer factor, Transcription factor LSF

1 Images
Western blot - Anti-CP2c antibody (AB155238)
  • WB

Unknown

Western blot - Anti-CP2c antibody (AB155238)

All lanes:

Western blot - Anti-CP2c antibody (ab155238) at 1/2000 dilution

All lanes:

Raji cell lysate at 30 µg

Predicted band size: 57 kDa

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Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human TFCP2 aa 1-200. The exact immunogen used to generate this antibody is proprietary information.

Q12800

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" }, "Chicken": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Xenopus laevis": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Xenopus tropicalis": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

CP2c also known as LSF or TFCP2 functions as a transcription factor involved in the regulation of gene expression. CP2c has a mass of approximately 37 kDa. It is expressed in various tissues with higher levels observed in the liver brain and lymphoid tissues. This protein is critical in influencing the expression of genes through direct binding to specific DNA sequences thereby altering transcriptional activities.
Biological function summary

CP2c serves as an important component in transcriptional regulation networks. It often functions as a part of multi-protein complexes interacting with co-activators or co-repressors to modulate target gene expression. CP2c plays significant roles in cell cycle control growth and differentiation by regulating genes involved in these biological processes.

Pathways

CP2c integrates into key regulatory networks impacting several important pathways such as cell cycle and nucleotide metabolism. In the context of the cell cycle CP2c interacts with proteins such as p53 and Rb which are essential in controlling cell division and DNA repair processes. These interactions help maintain normal cellular function and prevent unchecked cell proliferation.

CP2c links to conditions like cancer and viral infections. Its regulation of genes involved in cell proliferation is important in oncogenesis where dysregulated CP2c activity may contribute to tumor progression. In viral infections CP2c modulates the host cellular environment affecting how viruses replicate within host cells. Aberrant interactions with proteins like p53 reinforce the connection between CP2c and the development of cancer emphasizing the importance of this protein as a target for therapeutic intervention.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1 (By similarity). Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter.
See full target information TFCP2
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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

European journal of histochemistry : EJH 69: PubMed40985579

2025

miR-129-5p regulates HMGB1/RAGE axis to inhibit pyroptosis and ameliorate cervical epithelial cell deterioration.

Applications

Unspecified application

Species

Unspecified reactive species

Huafang Wang,Dilidaer Sidike,Pan Liu,Longge Suo,Huerxidan Niyazi

Cancers 15: PubMed37444605

2023

Prognostic Implication of YY1 and CP2c Expression in Patients with Primary Breast Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Chihwan David Cha,Seung Han Son,Chul Geun Kim,Hosub Park,Min Sung Chung

International journal of molecular sciences 23: PubMed35742810

2022

Structural and Functional Insights into CP2c Transcription Factor Complexes.

Applications

Unspecified application

Species

Unspecified reactive species

Seung Han Son,Min Young Kim,Eunbi Jo,Vladimir N Uversky,Chul Geun Kim
View all publications
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Product promise

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