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Rabbit Polyclonal CP2c antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human TFCP2 aa 1-200.

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Images

Western blot - Anti-CP2c antibody (AB155238), expandable thumbnail

Publications

Key facts

Isotype
IgG
Host species
Rabbit
Storage buffer

pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine

Form
Liquid
Clonality
Polyclonal

Immunogen

  • Recombinant Fragment Protein within Human TFCP2 aa 1-200. The exact immunogen used to generate this antibody is proprietary information. Database link Q12800

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
WB
Human
Tested
Chicken
Predicted
Cow
Predicted
Xenopus laevis
Predicted
Xenopus tropicalis
Predicted

Tested
Tested

Species
Human
Dilution info
1/500.00000 - 1/3000.00000
Notes

-

Predicted
Predicted

Species
Chicken, Cow, Xenopus laevis, Xenopus tropicalis
Dilution info
-
Notes

-

Target data

Function

Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1 (By similarity). Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter.

Alternative names

Recommended products

Rabbit Polyclonal CP2c antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human TFCP2 aa 1-200.

Key facts

Isotype
IgG
Form
Liquid
Clonality
Polyclonal
Immunogen
  • Recombinant Fragment Protein within Human TFCP2 aa 1-200. The exact immunogen used to generate this antibody is proprietary information. Database link Q12800
Purification technique
Affinity purification Immunogen
Concentration
Loading...

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.
Activity summary

CP2c also known as LSF or TFCP2 functions as a transcription factor involved in the regulation of gene expression. CP2c has a mass of approximately 37 kDa. It is expressed in various tissues with higher levels observed in the liver brain and lymphoid tissues. This protein is critical in influencing the expression of genes through direct binding to specific DNA sequences thereby altering transcriptional activities.

Biological function summary

CP2c serves as an important component in transcriptional regulation networks. It often functions as a part of multi-protein complexes interacting with co-activators or co-repressors to modulate target gene expression. CP2c plays significant roles in cell cycle control growth and differentiation by regulating genes involved in these biological processes.

Pathways

CP2c integrates into key regulatory networks impacting several important pathways such as cell cycle and nucleotide metabolism. In the context of the cell cycle CP2c interacts with proteins such as p53 and Rb which are essential in controlling cell division and DNA repair processes. These interactions help maintain normal cellular function and prevent unchecked cell proliferation.

Associated diseases and disorders

CP2c links to conditions like cancer and viral infections. Its regulation of genes involved in cell proliferation is important in oncogenesis where dysregulated CP2c activity may contribute to tumor progression. In viral infections CP2c modulates the host cellular environment affecting how viruses replicate within host cells. Aberrant interactions with proteins like p53 reinforce the connection between CP2c and the development of cancer emphasizing the importance of this protein as a target for therapeutic intervention.

Product promise

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1 product image

  • Western blot - Anti-CP2c antibody (ab155238), expandable thumbnail

    Western blot - Anti-CP2c antibody (ab155238)

    All lanes: Western blot - Anti-CP2c antibody (ab155238) at 1/2000 dilution

    All lanes: Raji cell lysate at 30 µg

    Developed using the ECL technique.

    Predicted band size: 57 kDa

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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