Rabbit Polyclonal CPAMD8 antibody. Suitable for IHC-P and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human CPAMD8 aa 850-1000.
Images
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Recombinant Fragment Protein within Human CPAMD8 aa 850-1000. The exact immunogen used to generate this antibody is proprietary information. Database link Q8IZJ3
Reactivity data
Select an application| IHC-P | |
|---|---|
| Human | Tested |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/10.00000 - 1/20.00000 | Notes Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target data
Alternative names
KIAA1283, CPAMD8, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8
Recommended products
Rabbit Polyclonal CPAMD8 antibody. Suitable for IHC-P and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human CPAMD8 aa 850-1000.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Recombinant Fragment Protein within Human CPAMD8 aa 850-1000. The exact immunogen used to generate this antibody is proprietary information. Database link Q8IZJ3
- Purification technique
- Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
CPAMD8 also known as Complement Component C3 and PZP-Like Alpha-2-Macroglobulin Domain Containing 8 is a protein characterized by a specific function in cellular processes. This protein has a molecular mass of approximately 215 kDa. Expression of CPAMD8 occurs in various tissues including eye and kidney suggesting its involvement in different physiological roles. Scientists have investigated this protein for its meaningful contributions to immune and structural systems.
- Biological function summary
CPAMD8 participates in immune regulation and structural organization within tissues. It performs tasks as part of a multiprotein complex interacting with other components to maintain cellular homeostasis. This protein influences processes that are essential for tissue integrity and immune responses where its activity affects cell adhesion and defense mechanisms.
- Pathways
CPAMD8 takes part in the complement system and extracellular matrix organization. It interacts with other key proteins such as Complement Component C9 and Laminins significantly impacting pathways involved in immune response modulation and structural framework stabilization. These interactions highlight the protein's role in maintaining immune and tissue health.
- Associated diseases and disorders
CPAMD8 has links with familial glaucoma and corneal dystrophies. Studies indicate that mutations or dysregulation of CPAMD8 can lead to these conditions often in association with proteins like MYOC (Myocilin) and TGFBI (Transforming Growth Factor Beta-Induced Protein). These connections underline the protein's importance in eye structure and function where its normal operation is important for preventing disease.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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1 product image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CPAMD8 antibody (ab122168)
ab122168 at 1/10 dilution staining CPAMD8 in Paraffin-embedded Human kidney tissue by Immunohistochemistry.
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