AB189182

Anti-Cpt1c/CPT1-B antibody

Name: Anti-Cpt1c/CPT1-B antibody (ab189182) | Abcam
Brand: Abcam Limited
SKU: AB189182
Price: 630 USD
Availability: InStock

(3 Reviews)

(5 Publications)

Goat Polyclonal Cpt1c/CPT1-B antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Synthetic Peptide within Human CPT1C aa 700 to C-terminus.

View Alternative Names

CATL1, CPT1C, Palmitoyl thioesterase CPT1C, Carnitine palmitoyltransferase 1C, Carnitine palmitoyltransferase I, CPTI-B, CPT I-C

2 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cpt1c/CPT1-B antibody (AB189182)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cpt1c/CPT1-B antibody (AB189182)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human testis tissue labeling Cpt1c/CPT1-B with ab189182 at 3.75 μg/ml.

Supplier Data

Western blot - Anti-Cpt1c/CPT1-B antibody (AB189182)

Primary incubation was 1 hour.

All lanes:

Western blot - Anti-Cpt1c/CPT1-B antibody (ab189182) at 1 µg/mL

All lanes:

Human frontal cortex lysate (in RIPA buffer) at 35 µg

Predicted band size: 91 kDa

Observed band size: 100 kDa

true

Key facts

Host species

Goat

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

Synthetic Peptide within Human CPT1C aa 700 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q8TCG5

Specificity

ab189182 is expected to recognise both reported isoforms (NP_689572.1; NP_001129524.1). Reported variants represent identical protein (NP_001186681.1; NP_001186682.1; NP_689572.1).

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "3.75 µg/mL", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1-3 µg/mL", "WB-species-notes": "<p></p>" }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Common marmoset": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Dog": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Gorilla": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Hamster": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Horse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Monkey": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Orangutan": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.3 Preservative: 0.02% Sodium azide Constituents: 99% Tris buffered saline, 0.5% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Palmitoyl thioesterase specifically expressed in the endoplasmic reticulum of neurons. Modulates the trafficking of the glutamate receptor, AMPAR, to plasma membrane through depalmitoylation of GRIA1 (PubMed : 30135643). Also regulates AMPR trafficking through the regulation of SACM1L phosphatidylinositol-3-phosphatase activity by interaction in a malonyl-CoA dependent manner (By similarity). Binds malonyl-CoA and couples malonyl-CoA to ceramide levels, necessary for proper spine maturation and contributing to systemic energy homeostasis and appetite control (PubMed : 16651524). Binds to palmitoyl-CoA, but does not have carnitine palmitoyltransferase 1 catalytic activity or at very low levels (PubMed : 25751282, PubMed : 30135643).

See full target information CPT1C

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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Journal of nanobiotechnology 22:506 PubMed39180102

2024

Preparation and characterization of BSA-loaded liraglutide and platelet fragment nanoparticle delivery system for the treatment of diabetic atherosclerosis.

Applications

Unspecified application

Species

Unspecified reactive species

Mingping He,Ming Fang,Limin Fan,Alimujiang Maimaitijiang

Molecular medicine reports 29: PubMed38299233

2024

Activation of AMPK pathway by low‑dose donafenib and atorvastatin combination improves high‑fat diet‑induced metabolic dysfunction‑associated steatotic liver disease.

Applications

Unspecified application

Species

Unspecified reactive species

Yaowei Bai,Kequan Chen,Jiacheng Liu,Yingliang Wang,Chaoyang Wang,Shuguang Ju,Chen Zhou,Wei Yao,Bin Xiong,Chuansheng Zheng

Nature chemical biology 18:698-705 PubMed35332331

2022

An infection-induced oxidation site regulates legumain processing and tumor growth.

Applications

Unspecified application

Species

Unspecified reactive species

Yekaterina Kovalyova,Daniel W Bak,Elizabeth M Gordon,Connie Fung,Jennifer H B Shuman,Timothy L Cover,Manuel R Amieva,Eranthie Weerapana,Stavroula K Hatzios

Evidence-based complementary and alternative medicine : eCAM 2021:8386848 PubMed34621326

2021

A Novel Identified Peptide Hormone "Metabolitin" Attenuates Lipid Absorption in the Small Intestine of Diabetic Mice with Nonalcoholic Fatty Liver Disease by Regulating Neurotensin and AMPK Signaling Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Peng Xu,Shanjuan Wang,Dongyue Pang

Cell death & disease 11:233 PubMed32300102

2020

MSC-induced lncRNA HCP5 drove fatty acid oxidation through miR-3619-5p/AMPK/PGC1α/CEBPB axis to promote stemness and chemo-resistance of gastric cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Honglei Wu,Bin Liu,Zhaosheng Chen,Guangchun Li,Zhen Zhang

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Cpt1c/CPT1-B antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cpt1c/CPT1-B antibody (AB189182)

Western blot - Anti-Cpt1c/CPT1-B antibody (AB189182)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Specificity

Complementary Products

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (5)

Product promise