JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB169543

Anti-CR1L antibody [EPR9604(B)]

Be the first to review this product! Submit a review

|

(1 Publication)

Rabbit Recombinant Monoclonal Crry antibody. Suitable for WB, Flow Cyt (Intra) and reacts with Human samples. Cited in 1 publication.

View Alternative Names

Complement component receptor 1-like protein, Complement C4b-binding protein CR-1-like protein, CR1L

2 Images
Flow Cytometry (Intracellular) - Anti-CR1L antibody [EPR9604(B)] (AB169543)
  • Flow Cyt (Intra)

Unknown

Flow Cytometry (Intracellular) - Anti-CR1L antibody [EPR9604(B)] (AB169543)

Intracellular flow cytometric analysis of permeabilized HepG2 cells labeling CR1L with ab169543 at 1/100 dilution (red) compared to a rabbit IgG (negative) (green).

Western blot - Anti-CR1L antibody [EPR9604(B)] (AB169543)
  • WB

Unknown

Western blot - Anti-CR1L antibody [EPR9604(B)] (AB169543)

All lanes:

Western blot - Anti-CR1L antibody [EPR9604(B)] (ab169543) at 1/1000 dilution

Lane 1:

HepG2 cell lysate at 10 µg

Lane 2:

Ramos cell lysate at 10 µg

Lane 3:

K562 cell lysate at 10 µg

Lane 4:

MOLT4 cell lysate at 10 µg

Secondary

All lanes:

Goat anti-rabbit HRP at 1/2000 dilution

Predicted band size: 63 kDa

false

  • Carrier free

    Anti-CR1L antibody [EPR9604(B)] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR9604(B)

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

Flow Cyt (Intra), WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

style
left-column

Complementary Products

Primary Antibodies

AB125011

Anti-TSG101 antibody [EPR7130(B)]

20ul selling size|BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry - Anti-TSG101 antibody [EPR7130(B)] (AB125011)

  • 4
  • 10
Primary Antibodies

AB150404

Anti-Zic2 antibody [EPR7790]

RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-Zic2 antibody [EPR7790] (AB150404)

  • 3
  • 2
Primary Antibodies

AB156011

Anti-ZNRF2 antibody [EPR11399(B)]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ZNRF2 antibody [EPR11399(B)] (AB156011)

  • 0
  • 0
Primary Antibodies

AB170885

Anti-ZNF92 antibody [EPR11514]

RabMAb|Recombinant

Western blot - Anti-ZNF92 antibody [EPR11514] (AB170885)

  • 0
  • 0
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "FlowCytIntra" : {"fullname" : "Flow Cytometry (Intracellular)", "shortname":"Flow Cyt (Intra)"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>", "FlowCytIntra-species-checked": "testedAndGuaranteed", "FlowCytIntra-species-dilution-info": "1/100 - 1/500", "FlowCytIntra-species-notes": "<p><a href='/en-us/products/primary-antibodies/rabbit-igg-monoclonal-epr25a-isotype-control-ab172730'>ab172730</a> - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.</p>", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }
style
left-column

Product details

Species reactivity
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species.
Please contact us for more information.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

style
left-column

Properties and storage information

Form
Liquid
Storage buffer
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

CR1L also known as CR1-like or C3b/C4b receptor 1-like is a protein encoded by the CR1L gene. This protein functions mechanically as a receptor that interacts specifically with complement components C3b and C4b playing roles in immune complex processing. The molecular mass of CR1L is approximately 130 kDa. Expression of CR1L occurs mostly in the liver certain cells of the hematopoietic lineage and in platelets.
Biological function summary

CR1L acts as part of the immune system by binding to complement fragments on opsonized pathogens which facilitates their clearance. It forms part of a receptor complex that clears immune complexes and helps in modulating the complement cascade. CR1L's involvement in complement regulation highlights its contribution to preventing excessive inflammation and protecting host tissues during immune defense.

Pathways

CR1L plays a significant role in the complement activation pathway specifically in classical and alternative pathways. These pathways involve proteins such as factor H and factor I which work alongside CR1L to ensure proper regulation of complement activity. By binding C3b and C4b CR1L helps in the breakdown of these components and assists in maintaining homeostasis by moderating complement activity.

CR1L associates with autoimmune conditions such as systemic lupus erythematosus and atypical hemolytic uremic syndrome. These disorders often involve dysregulation of complement activity. CR1L interacts with other complement regulatory proteins such as complement receptor 2 (CR2) in these contexts where imbalances in complement system function can lead to tissue damage and inflammation.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

See full target information CR1L
style
left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

International journal of medical sciences 22:3477-3489 PubMed40860777

2025

NDUFS1 upregulates ENaCα by NAD+ to promote alveolar fluid clearance in acute lung injury.

Applications

Unspecified application

Species

Unspecified reactive species

Mengmeng Wang,Mengting Chen,Jianping Zhu,Yu Zhang,Jian Lu,Zhiying Yue,Zhengfeng Yang,Ruilan Wang
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com