Rabbit Polyclonal CRISP3 antibody. Suitable for ELISA, WB, IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human Cysteine-rich secretory protein 3.
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% BSA
| ELISA | WB | IHC-P | |
|---|---|---|---|
| Human | Expected | Expected | Expected |
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info Use at an assay dependent concentration. | Notes - |
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info Use at an assay dependent concentration. | Notes - |
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info Use at an assay dependent concentration. | Notes - |
Cysteine-rich secretory protein 3, CRISP-3, Specific granule protein of 28 kDa, SGP28, CRISP3
Rabbit Polyclonal CRISP3 antibody. Suitable for ELISA, WB, IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human Cysteine-rich secretory protein 3.
Preservative: 0.02% Sodium azide
Constituents: PBS, 0.1% BSA
ab105951 recognizes both the N-glycosylated and non-glycosylated form of the mature protein.
0.2 µm filtered antibody solution
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CRISP3 also known as Cysteine-Rich Secretory Protein 3 is a protein key in various physiological processes. It typically weighs about 28 kDa. Found in a range of tissues but most prominently in the salivary glands pancreas and prostate. Researchers also detect CRISP3 in neutrophils. Its secretion to the extracellular environment after synthesis helps facilitate its functional roles. Scientists use ELISA assays to quantify its expression.
CRISP3 participates in host defense mechanisms and inflammation. It is a part of antimicrobial complexes that safeguard the body against microbial invasion. This protein can bind to other molecules and disrupt microbial membranes. It is believed to be involved in the innate immune response. CRISP3 also appears in granules of neutrophils where it functions during pathogen encounters.
CRISP3 interacts in immune response pathways that help buffer the body against pathogenic challenges. It aligns with the immune system's defense activities and might impact the signaling and regulatory pathways of inflammation. CRISP3's interactions with other proteins like defensins enhance its role in these immune pathways.
CRISP3 shows potential involvement in prostate cancer and Sjögren's syndrome. Its overexpression associates with prostate cancer progression and alterations in its levels might affect cancer-related proteins like PSA (prostate-specific antigen). In the context of Sjögren's syndrome CRISP3's expression changes may link to saliva secretion dysregulation impacting mucosal defense and inflammatory proteins involved in the disorder.
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This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
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