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AB192799

Anti-CRMP2 (phospho T509) antibody

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(2 Publications)

Rabbit Polyclonal CRMP2 phospho T509 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human DPYSL2 phospho T509 conjugated to Keyhole Limpet Haemocyanin.

View Alternative Names

CRMP2, ULIP2, DPYSL2, Dihydropyrimidinase-related protein 2, DRP-2, Collapsin response mediator protein 2, N2A3, Unc-33-like phosphoprotein 2, CRMP-2, ULIP-2

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CRMP2 (phospho T509) antibody (AB192799)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CRMP2 (phospho T509) antibody (AB192799)

Immunohistochemical analysis of paraffin-embedded human brain tissue labeling CRMP2 (phospho T509) with ab192799 at 1/50 (left) or ab192799 preincubated with blocking peptide (right).

Western blot - Anti-CRMP2 (phospho T509) antibody (AB192799)
  • WB

Supplier Data

Western blot - Anti-CRMP2 (phospho T509) antibody (AB192799)

All lanes:

Western blot - Anti-CRMP2 (phospho T509) antibody (ab192799) at 1/500 dilution

Lane 1:

HT29 cell extract

Lane 2:

HT29 cell extract with antigen-specific peptide

Predicted band size: 62 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

Synthetic Peptide within Human DPYSL2 phospho T509 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

Q16555

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/100", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

Product details

CRMP-2 is an enzyme with dihydropyrimidinase activity. Plays a role in RhoA-dependent signaling, through interaction with and regulation of Rho kinase. Plays a role in neurogenesis. Aberrantly expressed in fetal Down syndrome brain.

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
ab192799 was purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
Storage buffer
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.
See full target information DPYSL2 phospho T509

Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Communications biology 8:916 PubMed40527961

2025

Drug treatment alters performance in a neural microphysiological system of information processing.

Applications

Unspecified application

Species

Unspecified reactive species

Bradley Watmuff,Forough Habibollahi,Candice Desouza,Moein Khajehnejad,Alon Loeffler,Koby Baranes,Noah Poulin,Mark Kotter,Brett J Kagan

Molecular & cellular proteomics : MCP 22:100543 PubMed37030595

2023

N-Terminomic Changes in Neurons During Excitotoxicity Reveal Proteolytic Events Associated With Synaptic Dysfunctions and Potential Targets for Neuroprotection.

Applications

Unspecified application

Species

Unspecified reactive species

S Sadia Ameen,Nane Griem-Krey,Antoine Dufour,M Iqbal Hossain,Ashfaqul Hoque,Sharelle Sturgeon,Harshal Nandurkar,Dominik F Draxler,Robert L Medcalf,Mohd Aizuddin Kamaruddin,Isabelle S Lucet,Michael G Leeming,Dazhi Liu,Amardeep Dhillon,Jet Phey Lim,Faiza Basheer,Hong-Jian Zhu,Laita Bokhari,Carli L Roulston,Prasad N Paradkar,Oded Kleifeld,Andrew N Clarkson,Petrine Wellendorph,Giuseppe D Ciccotosto,Nicholas A Williamson,Ching-Seng Ang,Heung-Chin Cheng
View all publications

Product promise

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