Rabbit Polyclonal CRMP2 phospho T509 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human DPYSL2 phospho T509 conjugated to Keyhole Limpet Haemocyanin.
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- Molecular & cellular proteomics : MCP 22:1005432023N-Terminomic Changes in Neurons During Excitotoxicity Reveal Proteolytic Events Associated With Synaptic Dysfunctions and Potential Targets for Neuroprotection.Applications:Unspecified applicationReactive species:Unspecified reactive speciesS Sadia Ameen,Nane Griem-Krey,Antoine Dufour,M Iqbal Hossain,Ashfaqul Hoque,Sharelle Sturgeon,Harshal Nandurkar,Dominik F Draxler,Robert L Medcalf,Mohd Aizuddin Kamaruddin,Isabelle S Lucet,Michael G Leeming,Dazhi Liu,Amardeep Dhillon,Jet Phey Lim,Faiza Basheer,Hong-Jian Zhu,Laita Bokhari,Carli L Roulston,Prasad N Paradkar,Oded Kleifeld,Andrew N Clarkson,Petrine Wellendorph,Giuseppe D Ciccotosto,Nicholas A Williamson,Ching-Seng Ang,Heung-Chin ChengPubMed 37030595
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS, 0.87% Sodium chloride- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Synthetic Peptide within Human DPYSL2 phospho T509 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information. Database link Q16555
Reactivity data
Select an application| WB | IHC-P | |
|---|---|---|
| Human | Tested | Tested |
| Mouse | Predicted | Predicted |
| Rat | Predicted | Predicted |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/500 - 1/1000 | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Rat | Dilution info - | Notes - |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/50 - 1/100 | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Rat | Dilution info - | Notes - |
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Target data
Function
Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.
Alternative names
CRMP2, ULIP2, DPYSL2, Dihydropyrimidinase-related protein 2, DRP-2, Collapsin response mediator protein 2, N2A3, Unc-33-like phosphoprotein 2, CRMP-2, ULIP-2
Recommended products
Rabbit Polyclonal CRMP2 phospho T509 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human DPYSL2 phospho T509 conjugated to Keyhole Limpet Haemocyanin.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS, 0.87% Sodium chloride- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Synthetic Peptide within Human DPYSL2 phospho T509 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information. Database link Q16555
- Purification technique
- Affinity purification Immunogen
- Concentration
- Purification notes
ab192799 was purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
CRMP-2 is an enzyme with dihydropyrimidinase activity. Plays a role in RhoA-dependent signaling, through interaction with and regulation of Rho kinase. Plays a role in neurogenesis. Aberrantly expressed in fetal Down syndrome brain.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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2 product images
Western blot - Anti-CRMP2 (phospho T509) antibody (ab192799)
All lanes: Western blot - Anti-CRMP2 (phospho T509) antibody (ab192799) at 1/500 dilution
Lane 1: HT29 cell extract
Lane 2: HT29 cell extract with antigen-specific peptide
Predicted band size: 62 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CRMP2 (phospho T509) antibody (ab192799)
Immunohistochemical analysis of paraffin-embedded human brain tissue labeling CRMP2 (phospho T509) with ab192799 at 1/50 (left) or ab192799 preincubated with blocking peptide (right).
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