JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB150632

Anti-CRTH2 antibody

4

(2 Reviews)

|

(4 Publications)

Rabbit Polyclonal CRTH2 antibody. Suitable for IHC-P, ICC and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Synthetic Peptide within Human PTGDR2.

View Alternative Names

CD294, CRTH2, DL1R, GPR44, PTGDR2, Prostaglandin D2 receptor 2, Chemoattractant receptor-homologous molecule expressed on Th2 cells, G-protein coupled receptor 44

3 Images
Immunocytochemistry - Anti-CRTH2 antibody (AB150632)
  • ICC

Unknown

Immunocytochemistry - Anti-CRTH2 antibody (AB150632)

Immunocytochemical analysis of non-transfected HEK293 human embryonic kidney cells labeled with ab150632.

Immunocytochemistry - Anti-CRTH2 antibody (AB150632)
  • ICC

Unknown

Immunocytochemistry - Anti-CRTH2 antibody (AB150632)

Immunocytochemical analysis of HEK293 human embryonic kidney cells transfected with CRTH2, labeled with ab150632.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CRTH2 antibody (AB150632)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CRTH2 antibody (AB150632)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human nasal mucosa tissue (eosinophils) labeling CRTH2 with ab150632 at 32 μg/ml after heat-induced antigen retrieval.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, ICC

applications

Immunogen

Synthetic Peptide within Human PTGDR2. The exact immunogen used to generate this antibody is proprietary information.

Q9Y5Y4

Specificity

BLAST analysis of the peptide immunogen showed no homology with other human proteins.

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICC" : {"fullname" : "Immunocytochemistry", "shortname":"ICC"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "16-32 µg/mL", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval before commencing with IHC staining protocol.", "ICC-species-checked": "testedAndGuaranteed", "ICC-species-dilution-info": "", "ICC-species-notes": "<p></p>" }, "Dog": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICC-species-checked": "predicted", "ICC-species-dilution-info": "", "ICC-species-notes": "" }, "Gorilla": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICC-species-checked": "predicted", "ICC-species-dilution-info": "", "ICC-species-notes": "" }, "Monkey": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICC-species-checked": "predicted", "ICC-species-dilution-info": "", "ICC-species-notes": "" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
style
left-column
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
See full target information PTGDR2
style
left-column

Publications (4)

Recent publications for all applications. Explore the full list and refine your search

Technology in cancer research & treatment 24:15330338251353305 PubMed40551554

2025

Multimodal Model for Non-Invasive Detection of DRD2, SSTR2 and ESR1 Receptor Profiling in Pituitary Neuroendocrine Tumors: A Retrospective Study.

Applications

Unspecified application

Species

Unspecified reactive species

Jianglong Lu,Xianpeng Wang,Jinghao Jin,Fanjie Xu,Runhua Tang,Cheng Han,Zerui Wu,Zhipeng Su,Yuhang Guo

Annals of the rheumatic diseases 83:926-944 PubMed38325908

2024

Unveiling inflammatory and prehypertrophic cell populations as key contributors to knee cartilage degeneration in osteoarthritis using multi-omics data integration.

Applications

Unspecified application

Species

Unspecified reactive species

Yue Fan,Xuzhao Bian,Xiaogao Meng,Lei Li,Laiyi Fu,Yanan Zhang,Long Wang,Yan Zhang,Dalong Gao,Xiong Guo,Mikko Juhani Lammi,Guangdun Peng,Shiquan Sun

Frontiers in immunology 13:1046426 PubMed36466917

2022

Over-expression of CRTH2 indicates eosinophilic inflammation and poor prognosis in recurrent nasal polyps.

Applications

Unspecified application

Species

Unspecified reactive species

Wenhui Chen,Shaojuan He,Xinyu Xie,Xiaorong Yang,Chen Duan,Ping Ye,Xuezhong Li,Monica G Lawrence,Larry Borish,Xin Feng

Cell reports 36:109524 PubMed34380039

2021

Single-cell transcriptome analysis reveals the dynamics of human immune cells during early fetal skin development.

Applications

Unspecified application

Species

Unspecified reactive species

Yingping Xu,Jun Zhang,Yongfei Hu,Xuefei Li,Lihua Sun,Yu Peng,Yuzhe Sun,Bing Liu,Zhilei Bian,Zhili Rong
View all publications
style
left-column
style
left-column
style
right-column

Alternative Products

Primary Antibodies

AB190506

Anti-CRTH2 antibody

Western blot - Anti-CRTH2 antibody (AB190506)

  • 0
  • 0
Primary Antibodies

AB188998

Anti-CRTH2 antibody - N-terminal

Immunocytochemistry - Anti-CRTH2 antibody - N-terminal (AB188998)

  • 0
  • 0

Complementary Products

Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Primary Antibodies

AB302565

Anti-CD161 antibody [EPR26340-6] (BSA and Azide free)

BOND RX™ Validated|RabMAb|Advanced Validation|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD161 antibody [EPR26340-6] (BSA and Azide free) (AB302565)

  • 5
  • 2
Primary Antibodies

AB5103

Anti-Histone H3 (citrulline R2 + R8 + R17) antibody

Western blot - Anti-Histone H3 (citrulline R2 + R8 + R17) antibody (AB5103)

  • 4
  • 28
Primary Antibodies

AB208670

Anti-Myeloperoxidase antibody [EPR20257]

RabMAb|Recombinant|20ul selling size

Western blot - Anti-Myeloperoxidase antibody [EPR20257] (AB208670)

  • 5
  • 7

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com