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AB188998

Anti-CRTH2 antibody - N-terminal

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(1 Publication)

Rabbit Polyclonal CRTH2 antibody. N-terminal. Suitable for IHC-P, ICC and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human PTGDR2.

View Alternative Names

CD294, CRTH2, DL1R, GPR44, PTGDR2, Prostaglandin D2 receptor 2, Chemoattractant receptor-homologous molecule expressed on Th2 cells, G-protein coupled receptor 44

3 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CRTH2 antibody - N-terminal (AB188998)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CRTH2 antibody - N-terminal (AB188998)

Immunohistochemical analysis of formalin-fixed paraffin-embedded Human tonsil sections labeling CRTH2 using ab188998 at 10 μg/ml.

Immunocytochemistry - Anti-CRTH2 antibody - N-terminal (AB188998)
  • ICC

Supplier Data

Immunocytochemistry - Anti-CRTH2 antibody - N-terminal (AB188998)

Immunocytochemical analysis of CRTH2 transfected HEK293 cells labeling CRTH2 using ab188998.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CRTH2 antibody - N-terminal (AB188998)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CRTH2 antibody - N-terminal (AB188998)

Immunohistochemical analysis of formalin-fixed paraffin-embedded Human nasal mucosa sections (eosinophils) labeling CRTH2 using ab188998 at 10 μg/ml.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, ICC

applications

Immunogen

Synthetic Peptide within Human PTGDR2. The exact immunogen used to generate this antibody is proprietary information.

Q9Y5Y4

Specificity

BLAST analysis of the peptide immunogen showed no homology with other Human proteins.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICC" : {"fullname" : "Immunocytochemistry", "shortname":"ICC"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5-10 µg/mL", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval before commencing with IHC staining protocol.", "ICC-species-checked": "testedAndGuaranteed", "ICC-species-dilution-info": "", "ICC-species-notes": "<p></p>" }, "Gorilla": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICC-species-checked": "predicted", "ICC-species-dilution-info": "", "ICC-species-notes": "" }, "Monkey": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICC-species-checked": "predicted", "ICC-species-dilution-info": "", "ICC-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
See full target information PTGDR2
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Cancer & metabolism 13:31 PubMed40533847

2025

Obesity and cervical intraepithelial neoplasia: regulation of mitochondrial energy metabolism via the Kisspeptin/GPR54 signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Jiajia Pan,Yuanyuan Chen,Yan Ye,Peipei Li,Feifei Ni,Haizhen He
View all publications
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Product promise

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