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Rabbit Polyclonal CSN2 antibody. Suitable for WB, IHC-P and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human COP9 signalosome complex subunit 2 aa 1 to C-terminus.

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Images

Western blot - Anti-CSN2 antibody (AB155920), expandable thumbnail
  • Western blot - Anti-CSN2 antibody (AB155920), expandable thumbnail
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CSN2 antibody (AB155920), expandable thumbnail

Publications

Key facts

Isotype

IgG

Host species

Rabbit

Storage buffer

pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine)

Form

Liquid

Clonality

Polyclonal

Immunogen

  • Recombinant Fragment Protein within Human COP9 signalosome complex subunit 2 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link P61201

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
WBIHC-P
Human
Tested
Tested
Mouse
Tested
Expected
Rat
Predicted
Predicted
Chicken
Predicted
Predicted
Monkey
Predicted
Predicted
Pig
Predicted
Predicted
Xenopus laevis
Predicted
Predicted
Xenopus tropicalis
Predicted
Predicted
Zebrafish
Predicted
Predicted

Tested
Tested

Species

Mouse

Dilution info

1/5000.00000 - 1/20000.00000

Notes

-

Species

Human

Dilution info

1/5000.00000 - 1/20000.00000

Notes

-

Predicted
Predicted

Species

Rat, Chicken, Pig, Xenopus laevis, Monkey, Zebrafish, Xenopus tropicalis

Dilution info

-

Notes

-

Tested
Tested

Species

Human

Dilution info

1/100.00000 - 1/1000.00000

Notes

-

Expected
Expected

Species

Mouse

Dilution info

Use at an assay dependent concentration.

Notes

-

Predicted
Predicted

Species

Rat, Chicken, Pig, Xenopus laevis, Monkey, Zebrafish, Xenopus tropicalis

Dilution info

-

Notes

-

Associated Products

Select an associated product type

2 products for Alternative Product

Target data

Function

Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.

Alternative names

Recommended products

Rabbit Polyclonal CSN2 antibody. Suitable for WB, IHC-P and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human COP9 signalosome complex subunit 2 aa 1 to C-terminus.

Key facts

Isotype

IgG

Form

Liquid

Clonality

Polyclonal

Immunogen
  • Recombinant Fragment Protein within Human COP9 signalosome complex subunit 2 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link P61201
Purification technique

Affinity purification Immunogen

Concentration
Loading...

Storage

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

Notes

Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.

If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.

Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

3 product images

  • Western blot - Anti-CSN2 antibody (ab155920), expandable thumbnail

    Western blot - Anti-CSN2 antibody (ab155920)

    10% SDS PAGE

    All lanes: Western blot - Anti-CSN2 antibody (ab155920) at 1/10000 dilution

    Lane 1: 293T whole cell lysate at 30 µg

    Lane 2: A431 whole cell lysate at 30 µg

    Lane 3: HeLa whole cell lysate at 30 µg

    Lane 4: HepG2 whole cell lysate at 30 µg

    Predicted band size: 52 kDa

  • Western blot - Anti-CSN2 antibody (ab155920), expandable thumbnail

    Western blot - Anti-CSN2 antibody (ab155920)

    10% SDS PAGE

    All lanes: Western blot - Anti-CSN2 antibody (ab155920) at 1/5000 dilution

    Lane 1: NIH 3T3 whole cell lysate at 30 µg

    Lane 2: JC whole cell lysate at 30 µg

    Lane 3: BCL1 whole cell lysate at 30 µg

    Predicted band size: 52 kDa

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CSN2 antibody (ab155920), expandable thumbnail

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CSN2 antibody (ab155920)

    Immunohistochemical analysis of paraffin-embedded Human U87 xenograft tissue, labeling CSN2 with ab155920 at 1/500 dilution.

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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