Rabbit Polyclonal CSN2 antibody. Suitable for WB, IHC-P and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human COP9 signalosome complex subunit 2 aa 1 to C-terminus.
IgG
Rabbit
pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine)
Liquid
Polyclonal
WB | IHC-P | |
---|---|---|
Human | Tested | Tested |
Mouse | Tested | Expected |
Rat | Predicted | Predicted |
Chicken | Predicted | Predicted |
Monkey | Predicted | Predicted |
Pig | Predicted | Predicted |
Xenopus laevis | Predicted | Predicted |
Xenopus tropicalis | Predicted | Predicted |
Zebrafish | Predicted | Predicted |
Species | Dilution info | Notes |
---|---|---|
Species Mouse | Dilution info 1/5000.00000 - 1/20000.00000 | Notes - |
Species Human | Dilution info 1/5000.00000 - 1/20000.00000 | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Rat, Chicken, Pig, Xenopus laevis, Monkey, Zebrafish, Xenopus tropicalis | Dilution info - | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Human | Dilution info 1/100.00000 - 1/1000.00000 | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Mouse | Dilution info Use at an assay dependent concentration. | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Rat, Chicken, Pig, Xenopus laevis, Monkey, Zebrafish, Xenopus tropicalis | Dilution info - | Notes - |
Select an associated product type
Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.
CSN2, TRIP15, TRIP15, CSN2, COPS2, COP9 signalosome complex subunit 2, SGN2, Signalosome subunit 2, Alien homolog, JAB1-containing signalosome subunit 2, Thyroid receptor-interacting protein 15, TR-interacting protein 15, TRIP-15
Rabbit Polyclonal CSN2 antibody. Suitable for WB, IHC-P and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human COP9 signalosome complex subunit 2 aa 1 to C-terminus.
IgG
Rabbit
pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine)
Liquid
Polyclonal
Affinity purification Immunogen
Blue Ice
+4°C
-20°C
Upon delivery aliquot
Avoid freeze / thaw cycle
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10% SDS PAGE
All lanes: Western blot - Anti-CSN2 antibody (ab155920) at 1/10000 dilution
Lane 1: 293T whole cell lysate at 30 µg
Lane 2: A431 whole cell lysate at 30 µg
Lane 3: HeLa whole cell lysate at 30 µg
Lane 4: HepG2 whole cell lysate at 30 µg
Predicted band size: 52 kDa
10% SDS PAGE
All lanes: Western blot - Anti-CSN2 antibody (ab155920) at 1/5000 dilution
Lane 1: NIH 3T3 whole cell lysate at 30 µg
Lane 2: JC whole cell lysate at 30 µg
Lane 3: BCL1 whole cell lysate at 30 µg
Predicted band size: 52 kDa
Immunohistochemical analysis of paraffin-embedded Human U87 xenograft tissue, labeling CSN2 with ab155920 at 1/500 dilution.
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