Rabbit Polyclonal CTRP6 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human C1QTNF6 conjugated to Keyhole Limpet Haemocyanin.
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- Cancer cell international 21:6662021C1QTNF6 promotes oral squamous cell carcinoma by enhancing proliferation and inhibiting apoptosis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesXiaobin Song,Longjie Li,Liang Shi,Xinyu Liu,Xun Qu,Fengcai Wei,Ketao WangPubMed 34906149
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 99% PBS- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Synthetic Peptide within Human C1QTNF6 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information. Database link Q9BXI9
Reactivity data
Select an application| IHC-P | |
|---|---|
| Human | Tested |
| Mouse | Predicted |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 5 µg/mL | Notes Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info - | Notes - |
Associated Products
Select an associated product type
2 products for Alternative Product
Target data
Alternative names
CTRP6, UNQ581/PRO1151, C1QTNF6, Complement C1q tumor necrosis factor-related protein 6
Recommended products
Rabbit Polyclonal CTRP6 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human C1QTNF6 conjugated to Keyhole Limpet Haemocyanin.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 99% PBS- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Synthetic Peptide within Human C1QTNF6 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information. Database link Q9BXI9
- Purification technique
- Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- Avoid freeze / thaw cycle
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
CTRP6 also known as C1q/TNF-related protein 6 is a secreted protein that belongs to the C1q/TNF-related protein family. It has a molecular mass of approximately 37 kDa. Expression of CTRP6 occurs in various tissues including adipose tissue skeletal muscle and liver. Its structural components include a collagen-like domain and a C1q globular domain which are characteristic of proteins involved in immune responses and metabolic regulation.
- Biological function summary
CTRP6 plays a significant role in modulating inflammatory responses and metabolism. It acts by influencing the secretion and activity of cytokines such as IL-6 and TNF-alpha. Although not frequently noted as part of a multi-protein complex CTRP6 interacts closely with signaling molecules to achieve its functions. Studies suggest its involvement in maintaining metabolic balance and regulating insulin sensitivity key processes in various physiological states.
- Pathways
It interacts with several metabolic and inflammatory signaling cascades. This protein mediates effects through pathways like the AMPK signaling pathway which plays an important role in energy balance and metabolic stress responses. CTRP6 is also linked to the TLR4 signaling pathway involved in immune activation and inflammation. These pathways involve interactions with various proteins such as AMPK and TLR4 receptors highlighting its integrative role in cell signaling networks.
- Associated diseases and disorders
CTRP6 shows an association with conditions like obesity and type 2 diabetes. These diseases link to its role in regulating metabolic and inflammatory responses. Dysfunctional CTRP6 expression or activity has been observed in individuals with these metabolic disorders. Additionally CTRP6 relates to the expression and regulation of proteins such as adiponectin and TNF-alpha which are also involved in these disease pathways. These connections emphasize its potential as a therapeutic target for metabolic interventions.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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2 product images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CTRP6 antibody (ab115455)
ab115455, at 5 μg/ml, staining CTRP6 in formalin-fixed, paraffin-embedded Human Kidney tissue by Immunohistochemistry using a biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CTRP6 antibody (ab115455)
ab115455, at 5 µg/ml, staining CTRP6 in formalin-fixed, paraffin-embedded Human Small Intestine tissue by Immunohistochemistry using a biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
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