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AB201203

Anti-CWF19L2 antibody

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(1 Publication)

Rabbit Polyclonal CWF19L2 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human CWF19L2 aa 300-550.

View Alternative Names

CWF19-like protein 2, CWF19L2

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CWF19L2 antibody (AB201203)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CWF19L2 antibody (AB201203)

Immunohistochemical analysis of Formalin-fixed, Paraffin-embedded Human testis tissue labeling CWF19L2 with ab201203 at 1/100 dilution.

Western blot - Anti-CWF19L2 antibody (AB201203)
  • WB

Supplier Data

Western blot - Anti-CWF19L2 antibody (AB201203)

All lanes:

Western blot - Anti-CWF19L2 antibody (ab201203) at 1/1000 dilution

All lanes:

Human fetal liver lysate

Predicted band size: 104 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human CWF19L2 aa 300-550. The exact immunogen used to generate this antibody is proprietary information.

Q2TBE0

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/200 - 1/1000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/500", "IHCP-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Lyophilized
Reconstitution
reconstitute with water at 200µL
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

CWF19L2 also known as CWC19 Homolog 2 is a protein with a molecular mass of approximately 47 kDa. Mechanically this protein is involved in various cellular processes potentially including RNA splicing. CWF19L2 appears in multiple tissues but its expression is especially noticeable in the heart and prostate. Understanding its expression pattern provides insight into its potential roles in these tissues.
Biological function summary

It is engaging in processes that support cellular growth and function. CWF19L2 interacts as part of complex cellular machinery perhaps participating in the spliceosome complex which plays a role in RNA processing. This implies its involvement in important steps required for proper gene expression affecting cell survival and proliferation.

Pathways

CWF19L2 participates in key signaling and regulatory pathways such as the RNA splicing pathway and the mRNA processing pathway. It works alongside important proteins like SF3B1 and PRP8 within these pathways facilitating the correct maturation and regulation of mRNA. These pathways ensure that genetic information is accurately conveyed from DNA to proteins allowing cells to function properly.

Certain dysfunctions and mutations in CWF19L2 might relate to neurodegenerative diseases and certain forms of cancer. For example altered expression or mutations in CWF19L2 are associated with amyotrophic lateral sclerosis (ALS) where it may interact with proteins such as TDP-43. Such associations highlight the potential importance of CWF19L2 in cellular pathways that when disrupted lead to pathological states.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information CWF19L2
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of translational medicine 22:55 PubMed38218866

2024

Metabolic reprogramming based on RNA sequencing of gemcitabine-resistant cells reveals the FASN gene as a therapeutic for bladder cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Lijie Zhou,Kaixuan Du,Yiheng Dai,Youmiao Zeng,Yongbo Luo,Mengda Ren,Wenbang Pan,Yuanhao Liu,Lailai Zhang,Ronghui Zhu,Dapeng Feng,Fengyan Tian,Chaohui Gu
View all publications
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Product promise

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