Rabbit Polyclonal CXCL2 antibody. Suitable for ELISA, WB, sELISA and reacts with Mouse samples. Cited in 6 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Mouse Cxcl2.
View Alternative Names
Mip-2, Mip2, Scyb2, Cxcl2, C-X-C motif chemokine 2, Macrophage inflammatory protein 2, MIP2
Reactivity data
Properties and storage information
Form
Reconstitution
Purification technique
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
CXCL2 attracts and activates neutrophils as part of the innate immune response. It acts independently not as part of a larger complex to provoke a chemotactic response guiding neutrophils to areas of tissue injury. CXCL2 also promotes the release of other cytokines and enzymes that contribute to inflammation. Its activity is mediated through its interaction with receptors like CXCR2 on target cell surfaces.
Pathways
CXCL2 is involved in inflammatory signaling and leukocyte migration. It holds importance in the chemokine signaling pathway which regulates leukocyte trafficking. CXCL2 interacts with proteins like CXCR2 influencing the inflammation process by activating downstream kinases and other signal transduction molecules such as mitogen-activated protein kinases (MAPKs).
Product protocols
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Target data
Publications (6)
Recent publications for all applications. Explore the full list and refine your search
Journal of periodontology 93:1940-1950 PubMed35100435
2022
Applications
Unspecified application
Species
Unspecified reactive species
Experimental and therapeutic medicine 15:2356-2364 PubMed29456642
2018
Applications
Unspecified application
Species
Unspecified reactive species
Molecular medicine reports 14:2983-90 PubMed27510583
2016
Applications
Unspecified application
Species
Mouse
Journal of dental research 95:946-52 PubMed27013641
2016
Applications
Unspecified application
Species
Unspecified reactive species
Cellular microbiology 15:1419-26 PubMed23433011
2013
Applications
Unspecified application
Species
Unspecified reactive species
Biochemical and biophysical research communication 424:456-61 PubMed22771802
2012
Applications
Neut
Species
Unspecified reactive species
Product promise
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