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AB137792

Anti-CXCL9 antibody

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(4 Publications)

Rabbit Polyclonal CXCL9 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Synthetic Peptide within Human CXCL9 aa 50-100.

View Alternative Names

CMK, MIG, SCYB9, CXCL9, C-X-C motif chemokine 9, Gamma-interferon-induced monokine, Monokine induced by interferon-gamma, Small-inducible cytokine B9, HuMIG

3 Images
Immunocytochemistry/ Immunofluorescence - Anti-CXCL9 antibody (AB137792)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-CXCL9 antibody (AB137792)

A431 cells stained for MIG (green) using ab137792 at 1/1000 dilution in ICC/IF.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CXCL9 antibody (AB137792)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CXCL9 antibody (AB137792)

Paraffin embedded human lung adenocarcinoma tissue stained for CXCL9 using ab137792 at 1/250 dilution in immunohistochemical analysis.

Western blot - Anti-CXCL9 antibody (AB137792)
  • WB

Unknown

Western blot - Anti-CXCL9 antibody (AB137792)

12% SDS PAGE

All lanes:

Western blot - Anti-CXCL9 antibody (ab137792) at 1/1500 dilution

All lanes:

A431 whole cell lysate at 30 µg

Predicted band size: 14 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF, IHC-P, WB

applications

Immunogen

Synthetic Peptide within Human CXCL9 aa 50-100. The exact immunogen used to generate this antibody is proprietary information.

Q07325

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/1000", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/1000", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

CXCL9 also known as MIG (monokine induced by gamma interferon) is a small cytokine protein with a molecular weight of approximately 13 kDa. CXCL9 exhibits strong chemotactic properties and is secreted by various cells including endothelial cells macrophages and fibroblasts upon stimulation by interferon-gamma. Its expression primarily occurs in inflamed tissues and is associated with immune responses. Researchers often use tools like a CXCL9 ELISA kit or CXCL9 test to measure its expression levels in biological samples aiding in understanding its role in various conditions.
Biological function summary

This cytokine plays a pivotal role in the immune system by regulating leukocyte trafficking. CXCL9 exerts its function through binding to the CXCR3 receptor attracting T cells towards sites of inflammation or infection. This interaction is significant in mediating immune surveillance and host defense. CXCL9 does not form part of a larger protein complex but its chemokine activity is critical for immune system coordination. Scientific studies often highlight its involvement through CXCL9 function and expression analysis.

Pathways

CXCL9 significantly influences the chemokine signaling pathway and the Th1-type adaptive immune response. Within these pathways it interacts closely with other chemokines like CXCL10 and CXCL11 which also bind to the CXCR3 receptor. These pathways highlight the coordinated mobilization of T cells during immune challenges and inflammation emphasizing how CXCL9 is often examined alongside these related chemokines in research settings.

CXCL9 is notably associated with autoimmune diseases such as rheumatoid arthritis and inflammatory conditions like psoriasis. Its elevated expression is often observed in affected tissues contributing to disease pathogenesis through T cell migration and activation. In these contexts CXCL9 is frequently examined alongside other pro-inflammatory cytokines such as interferon-gamma and TNF-alpha which are known to modulate its expression and activity impacting disease progression and therapeutic strategies.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3.
See full target information CXCL9
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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

BMC biotechnology 25:30 PubMed40241108

2025

Parabacteroides distasonis promotes CXCL9 secretion of tumor-associated macrophages and enhances CD8T cell activity to trigger anti-tumor immunity against anti-PD-1 treatment in non-small cell lung cancer mice.

Applications

Unspecified application

Species

Unspecified reactive species

Zhijun Fan,Zheng Yi,Sheng Li,Junjun He

Discover oncology 16:131 PubMed39920513

2025

LAMB1 downregulation suppresses glioma progression by inhibiting aerobic glycolysis through regulation of the NF-κB/HK2 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Zhenxiang Zhao,Haiying Liu,Yingzi Liu,Junpeng Wen,Jiangwei Yuan

Frontiers in genetics 12:680413 PubMed34054929

2021

Identification of a Prognostic Signature for Ovarian Cancer Based on the Microenvironment Genes.

Applications

Unspecified application

Species

Unspecified reactive species

Xiao Huo,Hengzi Sun,Shuangwu Liu,Bing Liang,Huimin Bai,Shuzhen Wang,Shuhong Li

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 34:10778-10800 PubMed32619061

2020

Senescence-associated secretory phenotype promotes chronic ocular graft-vs-host disease in mice and humans.

Applications

Unspecified application

Species

Unspecified reactive species

Mio Yamane,Shinri Sato,Eisuke Shimizu,Shinsuke Shibata,Motoshi Hayano,Tomonori Yaguchi,Hajime Kamijuku,Mamoru Ogawa,Takanori Suzuki,Shin Mukai,Shigeto Shimmura,Hideyuki Okano,Tsutomu Takeuchi,Yutaka Kawakami,Yoko Ogawa,Kazuo Tsubota
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
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