AB193851

Anti-CXCL9 antibody

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(2 Publications)

Rabbit Polyclonal CXCL9 antibody. Suitable for sELISA and reacts with Recombinant full length protein - Cow, Cow samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Cow CXCL9.

View Alternative Names

C-X-C motif chemokine 9, Small-inducible cytokine B9, CXCL9

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Sandwich ELISA - Anti-CXCL9 antibody (AB193851)

sELISA

Supplier Data

Sandwich ELISA - Anti-CXCL9 antibody (AB193851)

Sandwich ELISA using ab193851. Wells were coated with 2.5 μg/mL of capture antibody ab193851 for 12-24 hours, followed by incubation with Recombinant Cow CXCL9 protein ab87521 for 2 hours. A biotinylated Rabbit anti-Cow CXCL9 polyclonal detection antibody was used at 0.1 μg/mL for 1 hour, followed by incubation with Streptavidin-HRP. TMB was added for 3 minutes and the optical density was read at 450 nm.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Cow

Applications

sELISA

applications

Immunogen

Recombinant Full Length Protein corresponding to Cow CXCL9.

A9QWP9

Specificity

This antibody has weak reactivity with equine, feline, mouse, and swine CXCL9.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "sELISA-species-checked": "notRecommended", "sELISA-species-dilution-info": "", "sELISA-species-notes": "" }, "Cow": { "sELISA-species-checked": "guaranteed", "sELISA-species-dilution-info": "1-5 µg/mL", "sELISA-species-notes": "" }, "Recombinant full length protein - Cow": { "sELISA-species-checked": "testedAndGuaranteed", "sELISA-species-dilution-info": "1-5 µg/mL", "sELISA-species-notes": "" } } }

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Product details

Cross-reactivity determined in ELISA.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

Preservative: 0.09% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

CXCL9 also known as MIG (monokine induced by gamma interferon) is a small cytokine protein with a molecular weight of approximately 13 kDa. CXCL9 exhibits strong chemotactic properties and is secreted by various cells including endothelial cells macrophages and fibroblasts upon stimulation by interferon-gamma. Its expression primarily occurs in inflamed tissues and is associated with immune responses. Researchers often use tools like a CXCL9 ELISA kit or CXCL9 test to measure its expression levels in biological samples aiding in understanding its role in various conditions.

Biological function summary

This cytokine plays a pivotal role in the immune system by regulating leukocyte trafficking. CXCL9 exerts its function through binding to the CXCR3 receptor attracting T cells towards sites of inflammation or infection. This interaction is significant in mediating immune surveillance and host defense. CXCL9 does not form part of a larger protein complex but its chemokine activity is critical for immune system coordination. Scientific studies often highlight its involvement through CXCL9 function and expression analysis.

Pathways

CXCL9 significantly influences the chemokine signaling pathway and the Th1-type adaptive immune response. Within these pathways it interacts closely with other chemokines like CXCL10 and CXCL11 which also bind to the CXCR3 receptor. These pathways highlight the coordinated mobilization of T cells during immune challenges and inflammation emphasizing how CXCL9 is often examined alongside these related chemokines in research settings.

CXCL9 is notably associated with autoimmune diseases such as rheumatoid arthritis and inflammatory conditions like psoriasis. Its elevated expression is often observed in affected tissues contributing to disease pathogenesis through T cell migration and activation. In these contexts CXCL9 is frequently examined alongside other pro-inflammatory cytokines such as interferon-gamma and TNF-alpha which are known to modulate its expression and activity impacting disease progression and therapeutic strategies.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

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Target data

Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3 (By similarity).

See full target information CXCL9

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Molecules (Basel, Switzerland) 26: PubMed33921211

2021

Multiplexed In Situ Protein Profiling with High-Performance Cleavable Fluorescent Tyramide.

Applications

Unspecified application

Species

Unspecified reactive species

Thai Pham,Renjie Liao,Joshua Labaer,Jia Guo

Medicine 99:e20944 PubMed32629699

2020

Inhibition of ITGB1 enhance the anti-tumor effect of cetuximab in colorectal cancer cell.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaohui Yang,Shuai Wang,Weihua Yu,Yixiong Zheng,Yulian Wu

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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Anti-CXCL9 antibody

Sandwich ELISA - Anti-CXCL9 antibody (AB193851)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Specificity

Reactivity data

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (2)

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