AB179446

Anti-CXorf23 antibody [EPR12942]

RabMAb
Recombinant
What is this?

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(1 Publication)

Rabbit Recombinant Monoclonal CXorf23 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication.

View Alternative Names

CXorf23, BCLAF3, BCLAF1 and THRAP3 family member 3

1 Images

Supplier Data

Western blot - Anti-CXorf23 antibody [EPR12942] (AB179446)

All lanes:

Western blot - Anti-CXorf23 antibody [EPR12942] (ab179446) at 1/1000 dilution

Lane 1:

Human skeletal muscle lysate at 10 µg

Lane 2:

Human cerebellum lysate at 10 µg

Lane 3:

Human placenta lysate at 10 µg

Lane 4:

HeLa lysate at 10 µg

Predicted band size: 84 kDa

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Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR12942

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

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Product details

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form

Liquid

Purity

Tissue culture supernatant

Storage buffer

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

CXorf23 is a protein encoded by the CXorf23 gene also known as Chromosome X Open Reading Frame 23. It has a molecular mass of approximately 31 kDa. Researchers have noted its expression in several tissues with significant levels occurring in the liver kidney and brain. Understanding its mechanical role provides insight into cellular processes and offers potential pathways for further research in cell biology.

Biological function summary

CXorf23 has roles related to cellular homeostasis and regulation. The protein does not show prominent participation in known protein complexes. Instead it interacts with various intracellular components suggesting a role in regulatory or signaling activities within cells. This function implies that proper expression or regulation of CXorf23 is necessary for maintaining normal cellular physiology.

Pathways

Researchers have identified that the expression of CXorf23 fits within immune response and metabolic regulation pathways. It shows associations with proteins involved in immune signaling pathways and energy metabolic pathways. CXorf23 may work alongside proteins like TNF-alpha in immune response modulation or with the metabolic regulators like AMPK providing a balanced cellular environment during metabolic stress.

Research links CXorf23 with autoimmune diseases and metabolic disorders. Abnormal expression or mutation of CXorf23 can lead to altered immune functions possibly affecting conditions like lupus. It also suggests associations with metabolic syndrome-related proteins indicating its potential involvement in obesity or diabetes-related pathways. Continued research is necessary to fully understand these connections and their implications on health.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

See full target information BCLAF3

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

The Journal of pathology 264:68-79 PubMed39022843

2024

Histone demethylase PHF8 promotes prostate cancer metastasis via the E2F1-SNAI1 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Ze Wang,Peng Tang,Haiyang Xiao,Song Peng,Jian Chen,Yapeng Wang,Jing Xu,Qian Yan,Junying Zhang,Jie Deng,Qiang Ma,Hailin Zhu,Weiming Luo,Dianzheng Zhang,Luofu Wang,Jun Qin,Weihua Lan,Jun Jiang,Qiuli Liu

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-CXorf23 antibody [EPR12942]

Western blot - Anti-CXorf23 antibody [EPR12942] (AB179446)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Product details

Properties and storage information

Form

Purity

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (1)

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Product promise