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AB69317

Anti-CXorf48 antibody

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(2 Publications)

Mouse Polyclonal CXorf48 antibody. Carrier free. Suitable for WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human CT55.

View Alternative Names

CXorf48, CT55, Cancer/testis antigen 55, Tumor antigen BJ-HCC-20

1 Images
Western blot - Anti-CXorf48 antibody (AB69317)
  • WB

Unknown

Western blot - Anti-CXorf48 antibody (AB69317)

All lanes:

Western blot - Anti-CXorf48 antibody (ab69317) at 1/500 dilution

Lane 1:

CXorf48 transfected 293T cell lysate at 25 µg

Lane 2:

Non-transfected 293T cell lysate at 25 µg

Secondary

All lanes:

Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Predicted band size: 29 kDa

Observed band size: 25 kDa

false

Key facts

Host species

Mouse

Clonality

Polyclonal

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human CT55.

Q8WUE5

Specificity

This antibody is reactive against mammalian transfected lysate.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Storage buffer
pH: 7.4 Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The CXorf48 also known as Chromosome X open reading frame 48 is a protein-coding gene that exhibits a molecular mass of approximately 20 kDa. Current research indicates that CXorf48 is expressed in several tissues including the testis and heart pointing to its conserved role across different biological processes. The function of CXorf48 is still not fully understood but it appears to be involved in cellular mechanisms that are relevant to the functionality of these tissues.
Biological function summary

The protein functionality provides insights into roles potentially impacting cellular behavior. CXorf48 might play a role in cellular structural organization or intracellular signaling. While not conclusively part of a large protein complex its interactions with various cellular components suggest a capacity for diverse biological effects. Studies continue to explore the biological implications of CXorf48 expression in human health and development.

Pathways

Ongoing investigations try to position CXorf48 within known biological pathways. Preliminary data suggests its involvement in pathways like signal transduction or cell cycle regulation. It might interact with key proteins such as kinases or phosphatases that regulate these processes although more research is needed to definitively map its pathway affiliations. Understanding these connections could shed light on how CXorf48 modulates broader cellular functions.

CXorf48 has associations with specific health conditions that relate to its expression levels or mutations. Research indicates potential links to conditions such as reproductive health disorders or cardiomyopathies. Associations with other proteins like androgen receptors or cardiac-related proteins could explain its involvement in these diseases providing a foundation for targeted investigations on its role in pathogenesis. This understanding may open avenues for therapeutic approaches targeting CXorf48.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Plays a role in spermatogenesis, possibly acting in the regulation of the autophagy pathway.
See full target information CT55
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Mitochondrion 64:19-26 PubMed35189384

2022

Cancer/Testis Antigen 55 is required for cancer cell proliferation and mitochondrial DNA maintenance.

Applications

Unspecified application

Species

Unspecified reactive species

Jade Aurrière,David Goudenege,Simone A Baechler,Shar-Yin N Huang,Naig Gueguen,Valerie Desquiret-Dumas,Floris Chabrun,Rodolphe Perrot,Arnaud Chevrollier,Majida Charif,Olivier R Baris,Yves Pommier,Guy Lenaers,Salim Khiati

Annals of botany 114:1385-97 PubMed25164699

2014

Structures formed by a cell membrane-associated arabinogalactan-protein on graphite or mica alone and with Yariv phenylglycosides.

Applications

Unspecified application

Species

Unspecified reactive species

Li Hong Zhou,Renate A Weizbauer,Srikanth Singamaneni,Feng Xu,Guy M Genin,Barbara G Pickard
View all publications
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Product promise

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