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AB251652

Anti-Cyclin K antibody

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(1 Publication)

Rabbit Polyclonal Cyclin K antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human CCNK aa 1-200.

View Alternative Names

CPR4, CCNK, Cyclin-K

1 Images
Immunocytochemistry/ Immunofluorescence - Anti-Cyclin K antibody (AB251652)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-Cyclin K antibody (AB251652)

PFA-fixed, Triton X-100 permeabilized MCF7 (human breast adenocarcinoma cell line) cells stained for Cyclin K (green) using ab251652 at 4 µg/ml in ICC/IF.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human CCNK aa 1-200. The exact immunogen used to generate this antibody is proprietary information.

O75909

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p>Fixation/Permeabilization: PFA/Triton X-100.</p>" }, "Mouse": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Regulatory subunit of cyclin-dependent kinases that mediates activation of target kinases. Plays a role in transcriptional regulation via its role in regulating the phosphorylation of the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A).
See full target information CCNK
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Nature 585:293-297 PubMed32494016

2020

The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K.

Applications

Unspecified application

Species

Unspecified reactive species

Mikołaj Słabicki,Zuzanna Kozicka,Georg Petzold,Yen-Der Li,Manisha Manojkumar,Richard D Bunker,Katherine A Donovan,Quinlan L Sievers,Jonas Koeppel,Dakota Suchyta,Adam S Sperling,Emma C Fink,Jessica A Gasser,Li R Wang,Steven M Corsello,Rob S Sellar,Max Jan,Dennis Gillingham,Claudia Scholl,Stefan Fröhling,Todd R Golub,Eric S Fischer,Nicolas H Thomä,Benjamin L Ebert
View all publications
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Product promise

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