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AB114086

Anti-Cyclin Y antibody

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(2 Publications)

Rabbit Polyclonal Cyclin Y antibody. Suitable for WB and reacts with Human, Mouse samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human CCNY.

View Alternative Names

C10orf9, CBCP1, CFP1, CCNY, Cyclin-Y, Cyc-Y, Cyclin box protein 1, Cyclin fold protein 1, cyclin-X

1 Images
Western blot - Anti-Cyclin Y antibody (AB114086)
  • WB

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Western blot - Anti-Cyclin Y antibody (AB114086)

All lanes:

Western blot - Anti-Cyclin Y antibody (ab114086) at 1 µg/mL

Lane 1:

HeLa whole cell lysate at 50 µg

Lane 2:

293T whole cell lysate at 50 µg

Lane 3:

NIH3T3 whole cell lysate at 50 µg

Lane 4:

MCF7 whole cell lysate at 50 µg

Predicted band size: 39 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

WB

applications

Immunogen

Synthetic Peptide within Human CCNY. The exact immunogen used to generate this antibody is proprietary information.

Q8ND76

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2500", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2496", "WB-species-notes": "<p></p>" }, "Bat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Chimpanzee": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Dog": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Gorilla": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Guinea pig": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Horse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Orangutan": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rabbit": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rhesus monkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
ab114086 was affinity purified using an epitope specific to Cyclin Y immobilized on solid support.
Storage buffer
pH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: 99% Tris citrate/phosphate
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.
See full target information CCNY
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Scientific reports 7:10228 PubMed28860486

2017

A systematic analysis of orphan cyclins reveals CNTD2 as a new oncogenic driver in lung cancer.

Applications

Unspecified application

Species

Unspecified reactive species

L Gasa,A Sanchez-Botet,E Quandt,S Hernández-Ortega,J Jiménez,M A Carrasco-García,S Simonetti,S J Kron,M P Ribeiro,E Nadal,A Villanueva,J Clotet

Oncology reports 36:2793-2799 PubMed27666310

2016

RNAi-mediated downregulation of cyclin Y to attenuate human breast cancer cell growth.

Applications

Unspecified application

Species

Unspecified reactive species

Feng Yan,Xiaoming Wang,Mingchen Zhu,Xiaoya Hu
View all publications
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Product promise

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