AB167513

Anti-Cyclophilin 40 antibody

Name: Anti-Cyclophilin 40 antibody (ab167513) | Abcam
Brand: Abcam Limited
SKU: AB167513

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(3 Publications)

Mouse Polyclonal Cyclophilin 40 antibody. Suitable for WB and reacts with Mouse, Rat, Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human PPID.

View Alternative Names

CYP40, CYPD, PPID, Peptidyl-prolyl cis-trans isomerase D, PPIase D, 40 kDa peptidyl-prolyl cis-trans isomerase, Cyclophilin-40, Cyclophilin-related protein, Rotamase D, CYP-40

5 Images

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Western blot - Anti-Cyclophilin 40 antibody (AB167513)

All lanes:

Western blot - Anti-Cyclophilin 40 antibody (ab167513) at 1 µg/mL

All lanes:

Raw 264.7 cell lysate at 50 µg

Secondary

All lanes:

Goat anti-Mouse IgG HRP at 1/2500 dilution

Predicted band size: 41 kDa

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Unknown

Western blot - Anti-Cyclophilin 40 antibody (AB167513)

All lanes:

Western blot - Anti-Cyclophilin 40 antibody (ab167513) at 1 µg/mL

All lanes:

K562 cell lysate at 50 µg

Secondary

All lanes:

Goat anti-Mouse IgG HRP at 1/2500 dilution

Predicted band size: 41 kDa

false

Unknown

Western blot - Anti-Cyclophilin 40 antibody (AB167513)

All lanes:

Western blot - Anti-Cyclophilin 40 antibody (ab167513) at 1 µg/mL

All lanes:

PC12 cell lysate at 50 µg

Secondary

All lanes:

Goat anti-Mouse IgG HRP at 1/2500 dilution

Predicted band size: 41 kDa

false

Unknown

Western blot - Anti-Cyclophilin 40 antibody (AB167513)

All lanes:

Western blot - Anti-Cyclophilin 40 antibody (ab167513) at 1 µg/mL

All lanes:

NIH3T3 cell lysate at 50 µg

Secondary

All lanes:

Goat anti-Mouse IgG HRP at 1/2500 dilution

Predicted band size: 41 kDa

false

Unknown

Western blot - Anti-Cyclophilin 40 antibody (AB167513)

All lanes:

Western blot - Anti-Cyclophilin 40 antibody (ab167513) at 1 µg/mL

Lane 1:

PPID transfected 293T cell lysate at 15 µL

Lane 2:

Non-transfected 293T cell lysate at 15 µL

Secondary

All lanes:

Goat anti-Mouse IgG HRP at 1/2500 dilution

Predicted band size: 41 kDa,42 kDa,45 kDa

false

Key facts

Host species

Mouse

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse, Rat, Human

Applications

applications

Immunogen

Recombinant Full Length Protein corresponding to Human PPID.

Q08752

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.4 Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding (PubMed : 11350175, PubMed : 20676357). Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control. May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes. May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus. May regulate MYB by inhibiting its DNA-binding activity. Involved in regulation of AHR signaling by promoting the formation of the AHR : ARNT dimer; the function is independent of HSP90 but requires the chaperone activity. Involved in regulation of UV radiation-induced apoptosis. Promotes cell viability in anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma (ALK+ ALCL) cell lines.. (Microbial infection) May be involved in hepatitis C virus (HCV) replication and release.

See full target information PPID

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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 16:6861 PubMed40715150

2025

Tumour initiated purinergic signalling promotes cardiomyocyte RBFOX1 degradation and cardiotoxicity from DNA damaging anticancer agents.

Applications

Unspecified application

Species

Unspecified reactive species

Saymon Tejay,Maria Areli Lorenzana-Carrillo,Guocheng Huang,Seyed Amirhossein Tabatabaei Dakhili,Yuan -Yuan Zhao,Farah Eaton,Michelle Mendiola Pla,Dawn E Bowles,Adam Kinnaird,D Ian Paterson,Edith Pituskin,John R Ussher,Evangelos D Michelakis,Gopinath Sutendra

Experimental and therapeutic medicine 24:662 PubMed36168411

2022

SIRT3 expression alleviates microglia activation‑induced dopaminergic neuron injury through the mitochondrial pathway.

Applications

Unspecified application

Species

Unspecified reactive species

De-Qi Jiang,Qing-Min Zang,Li-Lin Jiang,Cheng-Shu Lu,Shi-Hua Zhao,Lan-Cheng Xu

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 34:2128-36 PubMed25562160

2014

Desipramine ameliorates Cr(VI)-induced hepatocellular apoptosis via the inhibition of ceramide channel formation and mitochondrial PTP opening.

Applications

Unspecified application

Species

Unspecified reactive species

Lei Luo,Ying Xie,An Wang,Xinmin Liu,Fang Xiao,Xiali Zhong,Caigao Zhong

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Cyclophilin 40 antibody

Western blot - Anti-Cyclophilin 40 antibody (AB167513)

Western blot - Anti-Cyclophilin 40 antibody (AB167513)

Western blot - Anti-Cyclophilin 40 antibody (AB167513)

Western blot - Anti-Cyclophilin 40 antibody (AB167513)

Western blot - Anti-Cyclophilin 40 antibody (AB167513)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Complementary Products

Assay Kits

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Product protocols

Target data

Publications (3)

Product promise