Mouse Polyclonal Cyclophilin 40 antibody. Suitable for WB and reacts with Mouse, Rat, Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human PPID.
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Publications
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- Experimental and therapeutic medicine 24:6622022SIRT3 expression alleviates microglia activation‑induced dopaminergic neuron injury through the mitochondrial pathway.Applications:Unspecified applicationReactive species:Unspecified reactive speciesDe-Qi Jiang,Qing-Min Zang,Li-Lin Jiang,Cheng-Shu Lu,Shi-Hua Zhao,Lan-Cheng XuPubMed 36168411
- Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 34:2128-362014Desipramine ameliorates Cr(VI)-induced hepatocellular apoptosis via the inhibition of ceramide channel formation and mitochondrial PTP opening.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLei Luo,Ying Xie,An Wang,Xinmin Liu,Fang Xiao,Xiali Zhong,Caigao ZhongPubMed 25562160
Key facts
- Isotype
- IgG
- Host species
- Mouse
- Storage buffer
pH: 7.4
Constituents: 100% PBS- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Recombinant Full Length Protein corresponding to Human PPID. Database link Q08752
Reactivity data
Select an application| WB | |
|---|---|
| Human | Tested |
| Mouse | Tested |
| Rat | Tested |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info 1 µg/mL | Notes - |
Species Rat | Dilution info 1 µg/mL | Notes - |
Species Human | Dilution info 1 µg/mL | Notes - |
Target data
Function
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding (PubMed:11350175, PubMed:20676357). Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes. Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control. May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes. May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus. May regulate MYB by inhibiting its DNA-binding activity. Involved in regulation of AHR signaling by promoting the formation of the AHR:ARNT dimer; the function is independent of HSP90 but requires the chaperone activity. Involved in regulation of UV radiation-induced apoptosis. Promotes cell viability in anaplastic lymphoma kinase-positive anaplastic large-cell lymphoma (ALK+ ALCL) cell lines. (Microbial infection) May be involved in hepatitis C virus (HCV) replication and release.
Alternative names
CYP40, CYPD, PPID, Peptidyl-prolyl cis-trans isomerase D, PPIase D, 40 kDa peptidyl-prolyl cis-trans isomerase, Cyclophilin-40, Cyclophilin-related protein, Rotamase D, CYP-40
Recommended products
Mouse Polyclonal Cyclophilin 40 antibody. Suitable for WB and reacts with Mouse, Rat, Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human PPID.
Key facts
- Isotype
- IgG
- Host species
- Mouse
- Storage buffer
pH: 7.4
Constituents: 100% PBS- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Recombinant Full Length Protein corresponding to Human PPID. Database link Q08752
- Purification technique
- Affinity purification Protein A
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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5 product images
Western blot - Anti-Cyclophilin 40 antibody (ab167513)
All lanes: Western blot - Anti-Cyclophilin 40 antibody (ab167513) at 1 µg/mL
Lane 1: PPID transfected 293T cell lysate at 15 µL
Lane 2: Non-transfected 293T cell lysate at 15 µL
SecondaryAll lanes: Goat anti-Mouse IgG HRP at 1/2500 dilution
Predicted band size: 41 kDa, 42 kDa, 45 kDa
Western blot - Anti-Cyclophilin 40 antibody (ab167513)
All lanes: Western blot - Anti-Cyclophilin 40 antibody (ab167513) at 1 µg/mL
All lanes: PC12 cell lysate at 50 µg
SecondaryAll lanes: Goat anti-Mouse IgG HRP at 1/2500 dilution
Predicted band size: 41 kDa
Western blot - Anti-Cyclophilin 40 antibody (ab167513)
All lanes: Western blot - Anti-Cyclophilin 40 antibody (ab167513) at 1 µg/mL
All lanes: Raw 264.7 cell lysate at 50 µg
SecondaryAll lanes: Goat anti-Mouse IgG HRP at 1/2500 dilution
Predicted band size: 41 kDa
Western blot - Anti-Cyclophilin 40 antibody (ab167513)
All lanes: Western blot - Anti-Cyclophilin 40 antibody (ab167513) at 1 µg/mL
All lanes: NIH3T3 cell lysate at 50 µg
SecondaryAll lanes: Goat anti-Mouse IgG HRP at 1/2500 dilution
Predicted band size: 41 kDa
Western blot - Anti-Cyclophilin 40 antibody (ab167513)
All lanes: Western blot - Anti-Cyclophilin 40 antibody (ab167513) at 1 µg/mL
All lanes: K562 cell lysate at 50 µg
SecondaryAll lanes: Goat anti-Mouse IgG HRP at 1/2500 dilution
Predicted band size: 41 kDa
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