Rabbit Polyclonal CYP2A13 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human Cytochrome P450 2A13 aa 350-450.
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Cytochrome P450 2A13, CYPIIA13, CYP2A13
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CYP2A13 antibody (AB223785)
Paraffin-embedded human liver tissue stained for CYP2A13 using ab223785 at 1/50 dilution in immunohistochemical analysis.
Reactivity data
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Supplementary information
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Biological function summary
CYP2A13 influences the metabolic processing of xenobiotics. It belongs to the cytochrome P450 superfamily which is a group of enzymes essential for drug metabolism and the synthesis of cholesterol steroids and other lipids. While it does not form a complex itself it actively contributes to bioactivation processes that convert chemical compounds into reactive intermediates. This role is important for how the body handles and processes potential toxins or therapeutic drugs.
Pathways
The enzyme plays a notable role in the metabolism of xenobiotics by cytochrome P450. This pathway is key in converting lipophilic compounds into hydrophilic products for easier excretion. CYP2A13 is also involved in the metabolism of nicotine making it a part of the broader nicotine degradation pathway. It shares functional similarities with other cytochrome P450 family members like CYP2A6 which also participates in nicotine metabolism.
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Publications (1)
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Journal for immunotherapy of cancer 13: PubMed40954077
2025
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Species
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