Anti-Cytochrome P450 2E1 antibody
5
(6 Reviews)
|
(153 Publications)
Anti-Cytochrome P450 2E1 antibody (ab28146) is a rabbit polyclonal antibody detecting Cytochrome P450 2E1 in Western Blot. Suitable for Human, Mouse, Rabbit, Rat.
- Over 150 publications
- Trusted since 2006
View Alternative Names
Cyp2e, Cyp2e-1, Cyp2e1, Cytochrome P450 2E1, 4-nitrophenol 2-hydroxylase, CYPIIE1, Cytochrome P450-ALC, Cytochrome P450-J
- WB
AbReview25310****
Western blot - Anti-Cytochrome P450 2E1 antibody (AB28146)
All lanes:
Western blot - Anti-Cytochrome P450 2E1 antibody (ab28146) at 1/2500 dilution
All lanes:
Tissue lysate prepared from normal murine liver at 10 µg
Secondary
All lanes:
Goat anti-rabbit IgG-HRP at 1/5000 dilution
Predicted band size: 57 kDa
Observed band size: 55 kDa
true
Exposure time: 3s
Image courtesy of an anonymous Abreview.
- WB
Unknown
Western blot - Anti-Cytochrome P450 2E1 antibody (AB28146)
All lanes:
Western blot - Anti-Cytochrome P450 2E1 antibody (ab28146) at 1/1000 dilution
Lane 1:
Molecular weight marker
Lane 2:
Cell lysates prepared from human liver microsomes
Lane 3:
Cell lysates prepared from rat liver microsomes
Lane 4:
Cell lysates prepared from mouse liver microsomes
Lane 5:
Cell lysates prepared from rabbit liver microsomes
Predicted band size: 57 kDa
false
Reactivity data
Product details
Anti-Cytochrome P450 2E1 antibody (ab28146) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB) in Human, Mouse, Rabbit, Rat samples.
What is the molecular weight of Cytochrome P450 2E1?
Anti-Cytochrome P450 2E1 (ab28146) specifically detects a band for Cytochrome P450 2E1 (UniProt: P05181) at a molecular weight of 50-55kDa.
Trusted by the scientific community
Anti-Cytochrome P450 2E1 (ab28146) was first used in a scientific publication in 2006 and has been cited over 150 times in peer-reviewed journals.
Reviewed by scientists
Anti-Cytochrome P450 2E1 (ab28146) has over 5 independent reviews from customers.
Properties and storage information
Form
Purification technique
Storage buffer
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
The enzyme CYP2E1 metabolizes low-molecular-weight compounds. It catalyzes the conversion of substrates to more soluble forms enabling their excretion from the body. It is not a part of a larger protein complex but often partners with NADPH-cytochrome P450 reductase in electron transfer. CYP2E1 can also produce reactive oxygen species during its catalytic cycle which may impact cellular structures and processes.
Pathways
CYP2E1 is involved in the oxidative metabolism of ethanol and other xenobiotics. It participates in the metabolic pathways for drugs and carcinogens transforming them into either active or inactive metabolites. The enzyme has connections with other P450 enzymes such as CYP3A4 within the same metabolic landscape often overlapping substrates and regulatory mechanisms.
Product protocols
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Target data
Publications (153)
Recent publications for all applications. Explore the full list and refine your search
Antioxidants (Basel, Switzerland) 12: PubMed37891965
2023
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Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10:e2301096 PubMed37283464
2023
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Nature genetics 55:651-664 PubMed36914834
2023
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Science advances 9:eabq2937 PubMed36638165
2023
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Drug development research 84:211-225 PubMed36567664
2022
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Advanced biology 7:e2200208 PubMed36328790
2022
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Evidence-based complementary and alternative medicine : eCAM 2022:2481654 PubMed36285162
2022
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Journal of the American Society for Mass Spectrometry 33:2094-2107 PubMed36223142
2022
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International journal of molecular sciences 23: PubMed36232707
2022
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Alcohol (Fayetteville, N.Y.) 107:119-135 PubMed36150611
2022
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Product promise
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