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AB20203

Anti-Cytokeratin 5 + 14 antibody [LH8]

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(2 Publications)

Mouse Monoclonal Cytokeratin 14 antibody. Suitable for IHC-P, IHC-Fr and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human Keratin, type II cytoskeletal 5.

View Alternative Names

Cytokeratin-14, Keratin-14, CK-14, K14, KRT14

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

LH8

Isotype

IgM

Light chain type

unknown

Carrier free

No

Reacts with

Human

Applications

IHC-Fr, IHC-P

applications

Immunogen

Synthetic Peptide within Human Keratin, type II cytoskeletal 5. The exact immunogen used to generate this antibody is proprietary information.

P13647

Specificity

Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A/G
Storage buffer
Preservative: 0.02% Sodium azide Constituents: 99.98% PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.
See full target information Keratin, type I cytoskeletal 14

Additional targets

Keratin, type II cytoskeletal 5
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

PloS one 9:e94118 PubMed24705787

2014

Expression of RAGE and HMGB1 in thymic epithelial tumors, thymic hyperplasia and regular thymic morphology.

Applications

IHC-P

Species

Human

Bernhard Moser,Stefan Janik,Ana-Iris Schiefer,Leonhard Müllauer,Christine Bekos,Anke Scharrer,Michael Mildner,Ferenc Rényi-Vámos,Walter Klepetko,Hendrik Jan Ankersmit

Proceedings of the National Academy of Sciences of the United States of America 104:973-8 PubMed17210912

2007

Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma.

Applications

IHC-Fr

Species

Human

M E Prince,R Sivanandan,A Kaczorowski,G T Wolf,M J Kaplan,P Dalerba,I L Weissman,M F Clarke,L E Ailles
View all publications
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Product promise

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