AB17133

Anti-Cytokeratin 5 + 6 antibody [D5/16 B4]

Name: Anti-Cytokeratin 5 + 6 antibody [D5/16 B4] (ab17133) | Abcam
Brand: Abcam Limited
SKU: AB17133
Price: 250 USD
Availability: InStock
Rating: 4 (2 reviews)

(2 Reviews)

(13 Publications)

Mouse Monoclonal Cytokeratin 5 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 13 publications. Immunogen corresponding to Native Full Length Protein corresponding to Human KRT5.

View Alternative Names

58 kDa cytokeratin, Cytokeratin-5, Keratin-5, Type-II keratin Kb5, CK-5, K5, KRT5, CK5

1 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 5 + 6 antibody [D5/16 B4] (AB17133)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 5 + 6 antibody [D5/16 B4] (AB17133)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of Human tonsil tissue labeling Cytokeratin 5 + 6 with ab17133.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

D5/16 B4

Isotype

IgG1

Light chain type

kappa

Carrier free

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Native Full Length Protein corresponding to Human KRT5.

P13647

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/25 - 1/50", "IHCP-species-notes": "<p>Pretreat tissue with citrate buffer pH 6. Incubate with primary antibody for 30 minutes at room temperature.</p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Storage buffer

pH: 7.3 - 7.5 Preservative: 0.05% Sodium azide Constituents: 1% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Required for the formation of keratin intermediate filaments in the basal epidermis and maintenance of the skin barrier in response to mechanical stress (By similarity). Regulates the recruitment of Langerhans cells to the epidermis, potentially by modulation of the abundance of macrophage chemotactic cytokines, macrophage inflammatory cytokines and CTNND1 localization in keratinocytes (By similarity).

See full target information KRT5

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Publications (13)

Recent publications for all applications. Explore the full list and refine your search

Annals of medicine and surgery (2012) 86:2644-2650 PubMed38694326

2024

S100A6 could not promote the differentiation of Calu-6 lung cancer cell line.

Applications

Unspecified application

Species

Unspecified reactive species

Jie Li,Ting Wang,Dan Dang

Journal for immunotherapy of cancer 10: PubMed35338085

2022

Immunosuppressive tumor-associated macrophages expressing interlukin-10 conferred poor prognosis and therapeutic vulnerability in patients with muscle-invasive bladder cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Yijia Xu,Han Zeng,Kaifeng Jin,Zhaopei Liu,Yu Zhu,Le Xu,Zewei Wang,Yuan Chang,Jiejie Xu

Nature communications 12:3046 PubMed34031426

2021

Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics.

Applications

Unspecified application

Species

Unspecified reactive species

Ren-Bo Ding,Ping Chen,Barani Kumar Rajendran,Xueying Lyu,Haitao Wang,Jiaolin Bao,Jianming Zeng,Wenhui Hao,Heng Sun,Ada Hang-Heng Wong,Monica Vishnu Valecha,Eun Ju Yang,Sek Man Su,Tak Kan Choi,Shuiming Liu,Kin Iong Chan,Ling-Lin Yang,Jingbo Wu,Kai Miao,Qiang Chen,Joong Sup Shim,Xiaoling Xu,Chu-Xia Deng

Journal of cancer research and clinical oncology 145:2495-2506 PubMed31494736

2019

Validity of using immunohistochemistry to predict treatment outcome in patients with non-small cell lung cancer not otherwise specified.

Applications

Unspecified application

Species

Unspecified reactive species

Takahiro Ota,Keisuke Kirita,Reiko Matsuzawa,Hibiki Udagawa,Shingo Matsumoto,Kiyotaka Yoh,Seiji Niho,Genichiro Ishii,Koichi Goto

Matrix biology : journal of the International Soci 83:48-59 PubMed31302245

2019

Biallelic KRT5 mutations in autosomal recessive epidermolysis bullosa simplex, including a complete human keratin 5 "knock-out".

Applications

Unspecified application

Species

Unspecified reactive species

Hassan Vahidnezhad,Leila Youssefian,Maryam Daneshpazhooh,Hamidreza Mahmoudi,Ariana Kariminejad,Judith Fischer,Julie Christiansen,Holm Schneider,Alyson Guy,Lu Liu,John A McGrath,Cristina Has,Jouni Uitto

Molecular and cellular biology 39: PubMed30397077

2019

Senescent Breast Luminal Cells Promote Carcinogenesis through Interleukin-8-Dependent Activation of Stromal Fibroblasts.

Applications

Unspecified application

Species

Unspecified reactive species

Huda H Al-Khalaf,Hazem Ghebeh,Rabia Inass,Abdelilah Aboussekhra

Current problems in cancer 42:291-301 PubMed29731165

2018

Encapsulated papillary carcinoma of the breast: A clinicopathological study of 49 cases.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaomei Li,Yanmei Xu,Hong Ye,Shuming Qin,Feng Hou,Wenlou Liu

Scientific reports 8:2886 PubMed29440675

2018

In vitro patient-derived 3D mesothelioma tumor organoids facilitate patient-centric therapeutic screening.

Applications

Unspecified application

Species

Unspecified reactive species

Andrea R Mazzocchi,Shiny A P Rajan,Konstantinos I Votanopoulos,Adam R Hall,Aleksander Skardal

Oncology letters 14:5890-5898 PubMed29113223

2017

CD44/CD24 phenotype predicts a poor prognosis in triple-negative breast cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Hui Wang,Li Wang,Ying Song,Shuhuai Wang,Xu Huang,Qijia Xuan,Xinmei Kang,Qingyuan Zhang

Oncology letters 12:4505-4509 PubMed28105159

2016

Small bowel metastasis from pancreatic cancer in a long-term survival patient with synchronous advanced malignant pleural mesothelioma: A case report and literature review.

Applications

IHC-P

Species

Human

Morena Fasano,Carminia Maria Della Corte,Giovanni Vicidomini,Valerio Scotti,Pier Francesco Rambaldi,Alfonso Fiorelli,Marina Accardo,Ferdinando De Vita,Mario Santini,Fortunato Ciardiello,Floriana Morgillo

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Cytokeratin 5 + 6 antibody [D5/16 B4]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 5 + 6 antibody [D5/16 B4] (AB17133)

Key facts

Host species

Clonality

Clone number

Isotype

Light chain type

Carrier free

Reacts with

Applications

Immunogen

Complementary Products

Assay Kits

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Product protocols

Target data

Publications (13)

Product promise