AB238013

Anti-Cytokeratin 6a antibody [KRT6A/2368]

Name: Anti-Cytokeratin 6a antibody [KRT6A/2368] (ab238013) | Abcam
Brand: Abcam Limited
SKU: AB238013

Be the first to review this product! Submit a review

(3 Publications)

Mouse Monoclonal K2C6A antibody. Suitable for IHC-P, Protein Array and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human KRT6A.

View Alternative Names

K6A, KRT6D, KRT6A, Cytokeratin-6A, Cytokeratin-6D, Keratin-6A, Type-II keratin Kb6, CK-6A, CK-6D

4 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

Formalin-fixed, paraffin-embedded human prostate carcinoma tissue stained for Cytokeratin 6 using ab238013 at 2 μg/ml in immunohistochemical analysis.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

Formalin-fixed, paraffin-embedded human basal cell carcinoma tissue stained for Cytokeratin 6 using ab238013 at 2 μg/ml in immunohistochemical analysis.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

Formalin-fixed, paraffin-embedded human basal cell tissue stained for Cytokeratin 6 using ab238013 at 2 μg/ml in immunohistochemical analysis.

Protein Array - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

Protein Array

Unknown

Protein Array - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

ab238013 was tested in protein array against over 19000 different full-length human proteins.
Z- and S- Score : The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.
A MAb is specific to its intended target if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

KRT6A/2368

Isotype

IgG2a

Light chain type

kappa

Carrier free

Reacts with

Human

Applications

IHC-P, Protein Array

applications

Immunogen

Recombinant Full Length Protein corresponding to Human KRT6A.

P02538

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ProteinArray" : {"fullname" : "Protein Array", "shortname":"Protein Array"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1-2 µg/mL", "IHCP-species-notes": "<p>Incubate with primary antibody for 30 minutes at RT.</p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ProteinArray-species-checked": "testedAndGuaranteed", "ProteinArray-species-dilution-info": "", "ProteinArray-species-notes": "<p></p>" } } }

style

left-column

style

left-column

Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A/G

Purification notes

Purified from Bioreactor Concentrate by Protein A/G.

Storage buffer

pH: 7.2 - 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.05% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

style

left-column

style

left-column

style

left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

Target data

Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair.

See full target information KRT6A

style

left-column

Publications (3)

Recent publications for all applications. Explore the full list and refine your search

The Journal of investigative dermatology 143:2052-2064.e5 PubMed37044260

2023

Bacterial Pyocyanin Inducible Keratin 6A Accelerates Closure of Epithelial Defect under Conditions of Mitochondrial Dysfunction.

Applications

Unspecified application

Species

Unspecified reactive species

Subhadip Ghatak,Craig Hemann,James Boslett,Kanhaiya Singh,Anu Sharma,Mohamed S El Masry,Ahmed Safwat Abouhashem,Nandini Ghosh,Shomita S Mathew-Steiner,Sashwati Roy,Jay L Zweier,Chandan K Sen

Cell cycle (Georgetown, Tex.) 21:1479-1490 PubMed35311447

2022

expedites bladder cancer progression, regulated by miR-31-5p.

Applications

Unspecified application

Species

Unspecified reactive species

Yuan Chen,Shiben Ji,Jianxin Ying,Yongchang Sun,Jun Liu,Guohong Yin

Hepatology (Baltimore, Md.) 74:847-863 PubMed33554350

2021

The Clinical Significance of Hepatic CD69 CD103 CD8 Resident-Memory T Cells in Autoimmune Hepatitis.

Applications

Unspecified application

Species

Unspecified reactive species

Zhengrui You,You Li,Qixia Wang,Zhibin Zhao,Yikang Li,Qiwei Qian,Bo Li,Jun Zhang,Bingyuan Huang,Jubo Liang,Ruiling Chen,Zhuwan Lyu,Yong Chen,Min Lian,Xiao Xiao,Qi Miao,Jingyuan Fang,Zhexiong Lian,M Eric Gershwin,Ruqi Tang,Xiong Ma

View all publications

style

left-column

style

left-column

style

right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Cytokeratin 6a antibody [KRT6A/2368]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

Protein Array - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

Key facts

Host species

Clonality

Clone number

Isotype

Light chain type

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (3)

Alternative Products

Primary Antibodies

Complementary Products

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Product promise