Mouse Monoclonal GB antibody. Suitable for ICC/IF, Neut, IHC-Fr, ELISA and reacts with Human cytomegalovirus samples. Cited in 6 publications.
Images
![Immunocytochemistry/ Immunofluorescence - Anti-Cytomegalovirus Glycoprotein B antibody [HCMV37] (AB54023), expandable thumbnail](https://content.abcam.com/products/images/cytomegalovirus-glycoprotein-b-antibody-hcmv37-ab54023--immunocytochemistry-immunofluorescence-img135457.jpg/_jcr_content/renditions/webp-475.webp "Immunocytochemistry/ Immunofluorescence - Anti-Cytomegalovirus Glycoprotein B antibody [HCMV37] (AB54023)")
Publications
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- ACS sensors 5:147-1532020Nanoparticle Reservoirs for Paper-Only Immunosensors.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAlejandra Alba-Patiño et. al.PubMed 31850749
- Oncotarget 8:25989-259992016CMV70-3P miRNA contributes to the CMV mediated glioma stemness and represents a target for glioma experimental therapy.Applications:Unspecified applicationReactive species:Unspecified reactive speciesIlya V Ulasov,Natalya V Kaverina,Dhimankrishna Ghosh,Marya A Baryshnikova,Zaira G Kadagidze,Apollon I Karseladze,Anatoly Y Baryshnikov,Charles S CobbsPubMed 27517625
- Placenta 36:667-732015Viperin is induced following toll-like receptor 3 (TLR3) ligation and has a virus-responsive function in human trophoblast cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesB Wang et. al.PubMed 25814471
- Clinical and vaccine immunology : CVI 21:174-802013Enveloped virus-like particle expression of human cytomegalovirus glycoprotein B antigen induces antibodies with potent and broad neutralizing activity.Applications:NeutReactive species:Unspecified reactive speciesMarc Kirchmeier,Anne-Catherine Fluckiger,Catalina Soare,Jasminka Bozic,Barthelemy Ontsouka,Tanvir Ahmed,Abebaw Diress,Lenore Pereira,Florian Schödel,Stanley Plotkin,Charlotte Dalba,David Klatzmann,David E AndersonPubMed 24334684
- PloS one 7:e347952012Human cytomegalovirus entry into dendritic cells occurs via a macropinocytosis-like pathway in a pH-independent and cholesterol-dependent manner.Applications:ICC/IFReactive species:Unspecified reactive speciesFabienne Haspot et. al.PubMed 22496863
- The EMBO journal 5:3057-631986Identification of the human cytomegalovirus glycoprotein B gene and induction of neutralizing antibodies via its expression in recombinant vaccinia virus.Applications:Unspecified applicationReactive species:Unspecified reactive speciesM P Cranage,T Kouzarides,A T Bankier,S Satchwell,K Weston,P Tomlinson,B Barrell,H Hart,S E Bell,A C MinsonPubMed 3024973
Key facts
- Isotype
- IgG2a
- Host species
- Mouse
- Storage buffer
Preservative: 0.09% Sodium azide
Constituents: PBS- Form
- Liquid
- Clonality
- Monoclonal
Reactivity data
Select an application| ICC/IF | Neut | IHC-Fr | ELISA | |
|---|---|---|---|---|
| Human cytomegalovirus | Expected | Expected | Expected | Expected |
ICC/IF
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Human cytomegalovirus | Dilution info Use at an assay dependent concentration. | Notes - |
Neut
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Human cytomegalovirus | Dilution info Use at an assay dependent concentration. | Notes - |
IHC-Fr
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Human cytomegalovirus | Dilution info Use at an assay dependent concentration. | Notes - |
ELISA
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Human cytomegalovirus | Dilution info Use at an assay dependent concentration. | Notes - |
Associated Products
Select an associated product type
1 product for Alternative Product
Target data
Function
Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. May be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Participates also in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.
Alternative names
UL55, gB, Envelope glycoprotein B
Recommended products
Mouse Monoclonal GB antibody. Suitable for ICC/IF, Neut, IHC-Fr, ELISA and reacts with Human cytomegalovirus samples. Cited in 6 publications.
Key facts
- Isotype
- IgG2a
- Host species
- Mouse
- Storage buffer
Preservative: 0.09% Sodium azide
Constituents: PBS- Form
- Liquid
- Clonality
- Monoclonal
- Clone number
- HCMV37
- Purification technique
- Affinity purification Protein A
- Specificity
This antibody is specific for Cytomegalovirus glycoprotein B late neutralizing antigen. Reacts with MRC-5 infected cells but not uninfected cells.
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
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1 product image
![Immunocytochemistry/ Immunofluorescence - Anti-Cytomegalovirus Glycoprotein B antibody [HCMV37] (ab54023), expandable thumbnail](https://content.abcam.com/products/images/cytomegalovirus-glycoprotein-b-antibody-hcmv37-ab54023--immunocytochemistry-immunofluorescence-img135457.jpg "Immunocytochemistry/ Immunofluorescence - Anti-Cytomegalovirus Glycoprotein B antibody [HCMV37] (ab54023)")
Image from Haspot F et al., PLoS One. 2012;7(4):e34795. Epub 2012 Apr 9. Fig 2.; doi:10.1371/journal.pone.0034795; April 9, 2012, PLoS ONE 7(4): e34795.Immunocytochemistry/ Immunofluorescence - Anti-Cytomegalovirus Glycoprotein B antibody [HCMV37] (ab54023)
ab54023, staining Cytomegalovirus Glycoprotein B in monocyte-derived dendritic cells infected with Human cytomegalovirus (VHL/E strain), cultured for 3 hours (left panels) and 24 hours (right panels), by Immunocytochemistry/ Immunofluorescence.
Cells were fixed with paraformaldehyde and permeabilized with 0.2% Triton X-100 in PBS for 10 minutes at room temperature. Samples were incubated with primary antibody and an AlexaFluor®568-conjugated goat anti-mouse monoclonal IgG was used as the secondary antibody.
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