AB53489

Anti-Cytomegalovirus pp65 antibody [CH12]

Name: Anti-Cytomegalovirus pp65 antibody [CH12] (ab53489) | Abcam
Brand: Abcam Limited
SKU: AB53489
Price: 505 USD
Availability: InStock

Be the first to review this product! Submit a review

(9 Publications)

Mouse Monoclonal Cytomegalovirus pp65 antibody. Carrier free. Suitable for WB, ICC/IF and reacts with Human cytomegalovirus samples. Cited in 9 publications.

View Alternative Names

65 kDa phosphoprotein, pp65, 65 kDa matrix phosphoprotein, Phosphoprotein UL83, Tegument protein UL83, UL83

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

CH12

Isotype

IgG

Carrier free

Yes

Reacts with

Human cytomegalovirus

Applications

WB, ICC/IF

applications

Specificity

ab53489 is reactive with pp65 (UL83) of Cytomegalovirus.

style

left-column

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human cytomegalovirus": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "10 µg/mL", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "10 µg/mL", "ICCIF-species-notes": "<p></p>" } } }

style

left-column

style

left-column

Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Storage buffer

pH: 7.4 Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

style

left-column

style

left-column

style

left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

Target data

Counteracts the host antiviral immune response when activated and phosphorylated, by preventing host IRF3 from entering the nucleus (PubMed : 15452220). Also inhibits the type I interferon production by inactivating the enzymatic activity of DNA sensor CGAS without affecting STING1 (PubMed : 29263269, PubMed : 40243337). Participates in the transactivation of viral major immediate-early genes by the recruitment of host IFI16 to the promoters pf these genes (PubMed : 20504932).

See full target information UL83

style

left-column

Publications (9)

Recent publications for all applications. Explore the full list and refine your search

Allergologia et immunopathologia 53:36-44 PubMed40923418

2025

Knockdown of ARHGDIB promotes autophagy and reduces inflammation in LPS-induced alveolar epithelial cells via the PRKACB/NF-κB pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Haizhen Jin,Shuangxia Dong,Zhihui Li,Dai Xinjian

BioMed research international 2021:8835408 PubMed33959665

2021

Bilobalide Enhances AMPK Activity to Improve Liver Injury and Metabolic Disorders in STZ-Induced Diabetes in Immature Rats via Regulating HMGB1/TLR4/NF-B Signaling Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Meng Zhao,Jianpin Qin,Wenting Shen,Aiping Wu

Journal of cellular physiology 236:6726-6741 PubMed33611789

2021

HCMV modulates c-Mpl/IEX-1 pathway-mediated megakaryo/thrombopoiesis via PDGFRα and αvβ3 receptors after allo-HSCT.

Applications

Unspecified application

Species

Unspecified reactive species

Fei-Er Feng,Gao-Chao Zhang,Feng-Qi Liu,Yun He,Xiao-Lu Zhu,Xiao Liu,Yu Wang,Jing-Zhi Wang,Hai-Xia Fu,Yu-Hong Chen,Wei Han,Ying-Jun Chang,Lan-Ping Xu,Kai-Yan Liu,Xiao-Jun Huang,Xiao-Hui Zhang

International journal of molecular medicine 46:561-570 PubMed32468034

2020

MicroRNA‑93 contributes to the suppression of lung inflammatory responses in LPS‑induced acute lung injury in mice via the TLR4/MyD88/NF‑κB signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Hu Gao,Dongqiong Xiao,Linbo Gao,Xihong Li

Life sciences 239:116935 PubMed31610203

2019

Gastrodin combined with rhynchophylline inhibits cerebral ischaemia-induced inflammasome activation via upregulating miR-21-5p and miR-331-5p.

Applications

Unspecified application

Species

Unspecified reactive species

Heng-Sheng Zhang,Mei-Fang Liu,Xiong-Ying Ji,Chang-Rong Jiang,Zi-Li Li,Bo OuYang

Journal of virology 92: PubMed29769344

2018

Efficient Delivery of Human Cytomegalovirus T Cell Antigens by Attenuated Sendai Virus Vectors.

Applications

Unspecified application

Species

Unspecified reactive species

Richard Kiener,Markus Fleischmann,Marian Alexander Wiegand,Niels A W Lemmermann,Christiane Schwegler,Christine Kaufmann,Angelique Renzaho,Simone Thomas,Eva Felder,Hans Helmut Niller,Benedikt Asbach,Ralf Wagner

Scientific reports 8:1474 PubMed29367743

2018

Vaccine vectors based on Adenovirus 19a/64 exhibit broad cellular tropism and potently restimulate HCMV-specific T cell responses ex vivo.

Applications

Unspecified application

Species

Unspecified reactive species

Richard Kiener,Markus Fleischmann,Christiane Schwegler,Zsolt Ruzsics,Christian Thirion,Silke Schrödel,Benedikt Asbach,Ralf Wagner

Molecular medicine reports 15:3898-3904 PubMed28440401

2017

Relationship between T-cell receptor beta chain sequences and human cytomegalovirus infection in allogeneic hematopoietic stem cell transplant recipients.

Applications

Unspecified application

Species

Unspecified reactive species

Zhihua Wu,Huiping Zhang,Min Jin,Hanying Liang,Yaping Huang,Rong Yang,Genyong Gui,Huiqi Wang,Shengnan Gong,Jindong Wang,Jun Fan

Journal of immunology (Baltimore, Md. : 1950) 182:1548-59 PubMed19155503

2009

Cytomegalovirus-infected human endothelial cells can stimulate allogeneic CD4+ memory T cells by releasing antigenic exosomes.

Applications

Species

Unspecified reactive species

Jason D Walker,Cheryl L Maier,Jordan S Pober

View all publications

style

left-column

style

left-column

style

right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Cytomegalovirus pp65 antibody [CH12]

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Specificity

Alternative Products

Primary Antibodies

Complementary Products

Primary Antibodies

Primary Antibodies

Secondary Antibodies

Primary Antibodies

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (9)

Product promise