Rabbit Polyclonal Dab1 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Mouse, Rat, Human samples. Cited in 5 publications. Immunogen corresponding to Recombinant Fragment Protein within Human DAB1 aa 1-250.
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Publications
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- Molecular and cellular neurosciences 112:1036142021Defective Reelin/Dab1 signaling pathways associated with disturbed hippocampus development of homozygous yotari mice.Applications:Unspecified applicationReactive species:Unspecified reactive speciesNagisa Arimitsu,Yoshihisa Mizukami,Jun Shimizu,Kenji Takai,Tomoko Suzuki,Noboru SuzukiPubMed 33845123
- Cell cycle (Georgetown, Tex.) 19:2793-28102020Inhibition of microRNA-300 inhibits cell adhesion, migration, and invasion of prostate cancer cells by promoting the expression of .Applications:Unspecified applicationReactive species:Unspecified reactive speciesLin Li,Jing Hao,Cheng-Quan Yan,He-Feng Wang,Bin Meng,Sheng-Yong CaiPubMed 33064976
- Experimental neurology 320:1129702019Roles of Reelin/Disabled1 pathway on functional recovery of hemiplegic mice after neural cell transplantation; Reelin promotes migration toward motor cortex and maturation to motoneurons of neural grafts.Applications:Unspecified applicationReactive species:Unspecified reactive speciesNagisa Arimitsu,Kenji Takai,Naruyoshi Fujiwara,Jun Shimizu,Yuji Ueda,Sueshige Wakisaka,Chieko Hirotsu,Masanori A Murayama,Tomoko Suzuki,Noboru SuzukiPubMed 31185198
- PloS one 13:e02002682018Reelin controls the positioning of brainstem serotonergic raphe neurons.Applications:Unspecified applicationReactive species:Unspecified reactive speciesReham Shehabeldin,David Lutz,Meliha Karsak,Michael Frotscher,Kerstin Krieglstein,Ahmed SharafPubMed 30001399
- Cell and tissue research 359:393-4072014Localization of reelin signaling pathway components in murine midbrain and striatum.Applications:Unspecified applicationReactive species:MouseAhmed Sharaf,Belal Rahhal,Björn Spittau,Eleni RoussaPubMed 25418135
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine)- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Recombinant Fragment Protein within Human DAB1 aa 1-250. The exact immunogen used to generate this antibody is proprietary information. Database link O75553
Reactivity data
Select an application| IHC-P | WB | ICC/IF | |
|---|---|---|---|
| Human | Expected | Expected | Tested |
| Mouse | Tested | Tested | Expected |
| Rat | Expected | Tested | Expected |
| Chicken | Predicted | Predicted | Predicted |
| Pig | Predicted | Predicted | Predicted |
| Zebrafish | Predicted | Predicted | Predicted |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info 1/100 - 1/1000 | Notes Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Rat, Human | Dilution info Use at an assay dependent concentration. | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Chicken, Pig, Zebrafish | Dilution info - | Notes - |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info 1/500 - 1/3000 | Notes - |
Species Rat | Dilution info 1/500 - 1/3000 | Notes - |
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info Use at an assay dependent concentration. | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Chicken, Pig, Zebrafish | Dilution info - | Notes - |
ICC/IF
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/100 - 1/1000 | Notes - |
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Rat | Dilution info Use at an assay dependent concentration. | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Chicken, Pig, Zebrafish | Dilution info - | Notes - |
Associated Products
Select an associated product type
2 products for Alternative Product
Target data
Function
Signaling adapter of the reelin-mediated signaling pathway, which regulates the migration and differentiation of postmitotic neurons during brain development. Mediates intracellular transduction of Reelin signaling following reelin (RELN)-binding to its receptor: acts by docking proteins through its phosphotyrosine residues and PID domain.
Alternative names
Disabled homolog 1, DAB1
Recommended products
Rabbit Polyclonal Dab1 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Mouse, Rat, Human samples. Cited in 5 publications. Immunogen corresponding to Recombinant Fragment Protein within Human DAB1 aa 1-250.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine)- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Recombinant Fragment Protein within Human DAB1 aa 1-250. The exact immunogen used to generate this antibody is proprietary information. Database link O75553
- Purification technique
- Affinity purification Immunogen
- Concentration
- Purification notes
ab111684 is purified by antigen-affinity chromatography.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
4 product images
Immunocytochemistry/ Immunofluorescence - Anti-Dab1 antibody (ab111684)
HepG2 cells stained for DAB1 (green) using ab111684 at 1/500 dilution in ICC/IF.
Western blot - Anti-Dab1 antibody (ab111684)
7.5% SDS-PAGE
All lanes: Western blot - Anti-Dab1 antibody (ab111684) at 1/1000 dilution
Lane 1: Mouse brain tissue extract at 50 µg
Lane 2: Rat brain tissue extract at 50 µg
Predicted band size: 64 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Dab1 antibody (ab111684)
Paraffin embedded mouse duodenum tissue stained for DAB1 using ab111684 at 1/500 dilution in immunohistochemical analysis.
Western blot - Anti-Dab1 antibody (ab111684)
7.5% SDS-PAGE.
All lanes: Western blot - Anti-Dab1 antibody (ab111684) at 1/3000 dilution
All lanes: Mouse brain cell lysate at 50 µg
Predicted band size: 57 kDa, 60 kDa, 61 kDa, 62 kDa, 63 kDa, 64 kDa, 68 kDa, 69 kDa, 70 kDa, 71 kDa, 73 kDa, 74 kDa, 77 kDa, 79 kDa, 80 kDa, 84 kDa, 85 kDa, 87 kDa
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