AB133658

Anti-DcR1 antibody [EPR6162]

RabMAb
Recombinant
What is this?

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(3 Publications)

Rabbit Recombinant Monoclonal DcR1 antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 3 publications.

View Alternative Names

CD263, DCR1, LIT, TRAILR3, TRID, UNQ321/PRO366, TNFRSF10C, Tumor necrosis factor receptor superfamily member 10C, Antagonist decoy receptor for TRAIL/Apo-2L, Decoy TRAIL receptor without death domain, Decoy receptor 1, Lymphocyte inhibitor of TRAIL, TNF-related apoptosis-inducing ligand receptor 3, TRAIL receptor without an intracellular domain, DcR1, TRAIL receptor 3, TRAIL-R3

2 Images

Immunocytochemistry/ Immunofluorescence - Anti-DcR1 antibody [EPR6162] (AB133658)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-DcR1 antibody [EPR6162] (AB133658)

Immunofluorescent analysis of A549 cells labelling DcR1 with ab133658 at 1/100 dilution.

Unknown

Western blot - Anti-DcR1 antibody [EPR6162] (AB133658)

All lanes:

Western blot - Anti-DcR1 antibody [EPR6162] (ab133658) at 1/1000 dilution

Lane 1:

Human spleen lysate at 10 µg

Lane 2:

JAR cell lysate at 10 µg

Lane 3:

Human tonsil lysate at 10 µg

Lane 4:

Jurkat cell lysate at 10 µg

Lane 5:

A549 cell lysate at 10 µg

Lane 6:

Human fetal heart lysate at 10 µg

Secondary

All lanes:

HRP labelled goat anti-rabbit at 1/2000 dilution

Predicted band size: 27 kDa

false

Carrier free

Anti-DcR1 antibody [EPR6162] - BSA and Azide free
519 Alexa Fluor® 488

Alexa Fluor® 488 Anti-DcR1 antibody [EPR6162]
665 Alexa Fluor® 647

Alexa Fluor® 647 Anti-DcR1 antibody [EPR6162]

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR6162

Isotype

IgG

Carrier free

Reacts with

Human

Applications

ICC/IF, WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/250", "ICCIF-species-notes": "" }, "Mouse": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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Product details

This antibody was developed as part of a collaboration with the lab of Shi-Yong Sun at Emory University.

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form

Liquid

Storage buffer

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

Shipped at conditions

Conditional Ambient

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Storage information

Stable for 12 months at -20°C

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.

See full target information TNFRSF10C

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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in cellular neuroscience 14:192 PubMed32848609

2020

HIF-1α Mediates TRAIL-Induced Neuronal Apoptosis Regulating DcR1 Expression Following Traumatic Brain Injury.

Applications

Unspecified application

Species

Unspecified reactive species

Yuanjian Fang,Jianan Lu,Xiaoyu Wang,Haijian Wu,Shuhao Mei,Jingwei Zheng,Shenbin Xu,Cameron Lenahan,Sheng Chen,Jianmin Zhang,Yuan Hong

Frontiers in immunology 11:1072 PubMed32636833

2020

HTNV Sensitizes Host Toward TRAIL-Mediated Apoptosis-A Pivotal Anti-hantaviral Role of TRAIL.

Applications

Unspecified application

Species

Unspecified reactive species

Qing-Zhou Chen,Xin Wang,Fan Luo,Ning Li,Ni Zhu,Shuang Lu,Yu-Xing Zan,Chao-Jie Zhong,Mei-Rong Wang,Hai-Tao Hu,Yong-Zhen Zhang,Hai-Rong Xiong,Wei Hou

PloS one 14:e0214847 PubMed30947287

2019

Impact of p53 status on TRAIL-mediated apoptotic and non-apoptotic signaling in cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Anna Willms,Hella Schittek,Sascha Rahn,Justyna Sosna,Ufuk Mert,Dieter Adam,Anna Trauzold

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-DcR1 antibody [EPR6162]

Immunocytochemistry/ Immunofluorescence - Anti-DcR1 antibody [EPR6162] (AB133658)

Western blot - Anti-DcR1 antibody [EPR6162] (AB133658)

Related conjugates and formulations (3)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Product details

Properties and storage information

Form

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Product protocols

Target data

Publications (3)

Product promise