AB201080

Anti-DDX24 antibody

Name: Anti-DDX24 antibody (ab201080) | Abcam
Brand: Abcam Limited
SKU: AB201080

Be the first to review this product! Submit a review

(1 Publication)

Rabbit Polyclonal DDX24 antibody. Suitable for WB and reacts with Human, Mouse, Rat samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human DDX24 aa 50-150.

View Alternative Names

ATP-dependent RNA helicase DDX24, DEAD box protein 24, DDX24

1 Images

Supplier Data

Western blot - Anti-DDX24 antibody (AB201080)

All lanes:

Western blot - Anti-DDX24 antibody (ab201080)

Lane 1:

A549 whole cell lysate

Lane 2:

PC12 whole cell lysate

Lane 3:

sp20 whole cell lysate

Predicted band size: 96 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse, Rat, Human

Applications

applications

Immunogen

Synthetic Peptide within Human DDX24 aa 50-150. The exact immunogen used to generate this antibody is proprietary information.

Q9GZR7

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "" }, "Orangutan": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

style

left-column

style

left-column

Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.3 Preservative: 0.05% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

style

left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

DDX24 also known as DEAD-box helicase 24 is a member of the DEAD box protein family and functions as an ATP-dependent RNA helicase. This protein has a molecular mass of approximately 91 kDa. It is expressed in various tissues with notable levels seen in testis and heart. The expression pattern indicates its involvement in cellular processes that require tight regulation of RNA metabolism.

Biological function summary

DEAD-box helicases like DDX24 are important in RNA processing and ribosome biogenesis. DDX24 contributes to pre-rRNA processing by participating in the production and assembly of ribosomal subunits. The protein is also a part of the ribonucleoprotein complex where it influences the regulation of RNA interference processes. This suggests its essential role in RNA stability and gene expression regulation.

Pathways

DDX24 plays a significant role in the ribosome biogenesis pathway and RNA processing pathways. Both are fundamental for efficient protein synthesis. Within these pathways DDX24 interacts with other proteins like NOP56 and fibrillarin which are influential in the process of rRNA modification and folding. Such interactions are vital for the proper assembly of ribosomal subunits and their correct function in protein translation.

Dysregulation of DDX24 expression or function has been linked to certain cancers such as brain tumors where alterations in RNA processing are frequent. Moreover irregular DDX24 activity has been associated with viral infections such as HIV where the virus exploits host RNA processing machineries. This connection includes proteins like DDX6 which work with DDX24 during the viral replication cycle affecting the host's cellular environment and promoting disease progression.

style

left-column

style

left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

Target data

ATP-dependent RNA helicase.

See full target information DDX24

style

left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

EMBO reports 26:218-244 PubMed39609640

2024

The TGF-β mimic TGM4 achieves cell specificity through combinatorial surface co-receptor binding.

Applications

Unspecified application

Species

Unspecified reactive species

Shashi P Singh,Danielle J Smyth,Kyle T Cunningham,Ananya Mukundan,Chang-Hyeock Byeon,Cynthia S Hinck,Madeleine P J White,Claire Ciancia,Natalia Wąsowska,Anna Sanders,Regina Jin,Ruby F White,Sergio Lilla,Sara Zanivan,Christina Schoenherr,Gareth J Inman,Maarten van Dinther,Peter Ten Dijke,Andrew P Hinck,Rick M Maizels

View all publications

style

left-column

style

left-column

style

right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-DDX24 antibody

Western blot - Anti-DDX24 antibody (AB201080)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (1)

Alternative Products

Primary Antibodies

Primary Antibodies

Complementary Products

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Product promise