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AB195172

Anti-Deadpan antibody [11D1CH11]

4

(1 Review)

|

(15 Publications)

Rat Monoclonal Deadpan antibody. Suitable for IHC and reacts with Drosophila melanogaster samples. Cited in 15 publications.

View Alternative Names

CG8704, dpn, Protein deadpan

1 Images
Immunohistochemistry - Anti-Deadpan antibody [11D1CH11] (AB195172)
  • IHC

Supplier Data

Immunohistochemistry - Anti-Deadpan antibody [11D1CH11] (AB195172)

Immunohistochemistry analysis Drosophila stage 11 embryo labeling Deadpan with ab195172 at 10 μg/mL, followed by Alexa405 conjugated goat anti-rat secondary (at 10μg/mL).

Key facts

Host species

Rat

Clonality

Monoclonal

Clone number

11D1CH11

Isotype

IgG2b

Light chain type

kappa

Carrier free

No

Reacts with

Drosophila melanogaster

Applications

IHC

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHC" : {"fullname" : "Immunohistochemistry", "shortname":"IHC"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Drosophila melanogaster": { "IHC-species-checked": "testedAndGuaranteed", "IHC-species-dilution-info": "", "IHC-species-notes": "<p></p>" } } }
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Product details

Want a custom formulation?
This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com
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Properties and storage information

Form
Liquid
Purification notes
>95% based on SDS-PAGE
Storage buffer
pH: 7.5 Preservative: 0.02% Sodium azide Constituents: 99% HEPES buffered saline
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Do Not Freeze
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Transcriptional repressor of genes that require a bHLH protein for their transcription (PubMed : 1427077, PubMed : 24618901, PubMed : 28899667). In the larval brain, required to maintain the self-renewal and identity of type II neuroblasts by regulating the expression of the transcriptional repressor erm together with other self-renewal transcriptional repressors such as klu and E(spl)mgamma-HLH (PubMed : 21262215, PubMed : 22357926, PubMed : 23056424, PubMed : 24618901, PubMed : 28899667). As part of its role in neuroblasts development, has been shown to be a direct target of the Notch signaling pathway, however might work also independently of N/Notch (PubMed : 21262215, PubMed : 22357926, PubMed : 23056424). In the developing larval and pupal brain, required for mushroom body differentiation (PubMed : 22357926). Involved in sex determination and SXL transcription repression when in complex with the corepressor protein Groucho (PubMed : 7651341, PubMed : 8001118).
See full target information dpn
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Publications (15)

Recent publications for all applications. Explore the full list and refine your search

PLoS genetics 21:e1011586 PubMed39913561

2025

The transmembrane protein Syndecan is required for stem cell survival and maintenance of their nuclear properties.

Applications

Unspecified application

Species

Unspecified reactive species

Buffy L Eldridge-Thomas,Jerome G Bohere,Chantal Roubinet,Alexandre Barthelemy,Tamsin J Samuels,Felipe Karam Teixeira,Golnar Kolahgar

Nature communications 15:5097 PubMed38877037

2024

Dan forms condensates in neuroblasts and regulates nuclear architecture and progenitor competence in vivo.

Applications

Unspecified application

Species

Unspecified reactive species

Gillie Benchorin,Richard Jangwon Cho,Maggie Jiaqi Li,Natalia Molotkova,Minoree Kohwi

Methods in molecular biology (Clifton, N.J.) 2740:229-242 PubMed38393479

2024

Imaging and Analysis of Drosophila Neural Stem Cell Asymmetric Division.

Applications

Unspecified application

Species

Unspecified reactive species

Anne-Marie Berisha,Gregory Eot-Houllier,Régis Giet

Life science alliance 6: PubMed37495395

2023

Dissecting morphogenetic apoptosis through a genetic screen in Drosophila.

Applications

Unspecified application

Species

Unspecified reactive species

Audrey Barbaste,Sonia Schott,Corinne Benassayag,Magali Suzanne

Annals of clinical and translational neurology 9:1276-1288 PubMed35871307

2022

ANKLE2-related microcephaly: A variable microcephaly syndrome resembling Zika infection.

Applications

Unspecified application

Species

Unspecified reactive species

Ajay X Thomas,Nichole Link,Laurie A Robak,Gail Demmler-Harrison,Emily C Pao,Audrey E Squire,Savannah Michels,Julie S Cohen,Anne Comi,Paolo Prontera,Alberto Verrotti di Pianella,Giuseppe Di Cara,Livia Garavelli,Stefano Giuseppe Caraffi,Carlo Fusco,Roberta Zuntini,Kendall C Parks,Elliott H Sherr,Mais O Hashem,Sateesh Maddirevula,Fowzan S Alkuraya,Isphana A F Contractar,Jennifer E Neil,Christopher A Walsh,Hugo J Bellen,Hsiao-Tuan Chao,Robin D Clark,Ghayda M Mirzaa

Developmental cell 56:2649-2663.e6 PubMed34529940

2021

Discrete cis-acting element regulates developmentally timed gene-lamina relocation and neural progenitor competence in vivo.

Applications

Unspecified application

Species

Unspecified reactive species

Tanguy Lucas,Terry L Hafer,Harrison G Zhang,Natalia Molotkova,Minoree Kohwi

Developmental cell : PubMed33535069

2021

Arp2/3-dependent mechanical control of morphogenetic robustness in an inherently challenging environment.

Applications

Unspecified application

Species

Unspecified reactive species

Emmanuel Martin,Sophie Theis,Guillaume Gay,Bruno Monier,Christian Rouvière,Magali Suzanne

Developmental cell 51:713-729.e6 PubMed31735666

2019

Mutations in ANKLE2, a ZIKA Virus Target, Disrupt an Asymmetric Cell Division Pathway in Drosophila Neuroblasts to Cause Microcephaly.

Applications

Unspecified application

Species

Unspecified reactive species

Nichole Link,Hyunglok Chung,Angad Jolly,Marjorie Withers,Burak Tepe,Benjamin R Arenkiel,Priya S Shah,Nevan J Krogan,Hatip Aydin,Bilgen B Geckinli,Tulay Tos,Sedat Isikay,Beyhan Tuysuz,Ganesh H Mochida,Ajay X Thomas,Robin D Clark,Ghayda M Mirzaa,James R Lupski,Hugo J Bellen

Biology open 8: PubMed30948355

2019

Distinct gene-selective roles for a network of core promoter factors in neural stem cell identity.

Applications

Unspecified application

Species

Unspecified reactive species

Alexandre Neves,Robert N Eisenman

Cell 175:1931-1945.e18 PubMed30550790

2018

Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Priya S Shah,Nichole Link,Gwendolyn M Jang,Phillip P Sharp,Tongtong Zhu,Danielle L Swaney,Jeffrey R Johnson,John Von Dollen,Holly R Ramage,Laura Satkamp,Billy Newton,Ruth Hüttenhain,Marine J Petit,Tierney Baum,Amanda Everitt,Orly Laufman,Michel Tassetto,Michael Shales,Erica Stevenson,Gabriel N Iglesias,Leila Shokat,Shashank Tripathi,Vinod Balasubramaniam,Laurence G Webb,Sebastian Aguirre,A Jeremy Willsey,Adolfo Garcia-Sastre,Katherine S Pollard,Sara Cherry,Andrea V Gamarnik,Ivan Marazzi,Jack Taunton,Ana Fernandez-Sesma,Hugo J Bellen,Raul Andino,Nevan J Krogan
View all publications
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Product promise

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