Rat Monoclonal Deadpan antibody. Suitable for IHC and reacts with Drosophila melanogaster samples. Cited in 12 publications.
Images
![Immunohistochemistry - Anti-Deadpan antibody [11D1CH11] (AB195172), expandable thumbnail](https://content.abcam.com/products/images/deadpan-antibody-11d1ch11-ab195172--immunohistochemistry-img77435.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry - Anti-Deadpan antibody [11D1CH11] (AB195172)")
Publications
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- Life science alliance 6:2023Dissecting morphogenetic apoptosis through a genetic screen in Drosophila.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAudrey Barbaste,Sonia Schott,Corinne Benassayag,Magali SuzannePubMed 37495395
- Annals of clinical and translational neurology 9:1276-12882022ANKLE2-related microcephaly: A variable microcephaly syndrome resembling Zika infection.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAjay X Thomas,Nichole Link,Laurie A Robak,Gail Demmler-Harrison,Emily C Pao,Audrey E Squire,Savannah Michels,Julie S Cohen,Anne Comi,Paolo Prontera,Alberto Verrotti di Pianella,Giuseppe Di Cara,Livia Garavelli,Stefano Giuseppe Caraffi,Carlo Fusco,Roberta Zuntini,Kendall C Parks,Elliott H Sherr,Mais O Hashem,Sateesh Maddirevula,Fowzan S Alkuraya,Isphana A F Contractar,Jennifer E Neil,Christopher A Walsh,Hugo J Bellen,Hsiao-Tuan Chao,Robin D Clark,Ghayda M MirzaaPubMed 35871307
- Developmental cell 56:2649-2663.e62021Discrete cis-acting element regulates developmentally timed gene-lamina relocation and neural progenitor competence in vivo.Applications:Unspecified applicationReactive species:Unspecified reactive speciesTanguy Lucas,Terry L Hafer,Harrison G Zhang,Natalia Molotkova,Minoree KohwiPubMed 34529940
- Developmental cell :2021Arp2/3-dependent mechanical control of morphogenetic robustness in an inherently challenging environment.Applications:Unspecified applicationReactive species:Unspecified reactive speciesEmmanuel Martin et. al.PubMed 33535069
- Developmental cell 51:713-729.e62019Mutations in ANKLE2, a ZIKA Virus Target, Disrupt an Asymmetric Cell Division Pathway in Drosophila Neuroblasts to Cause Microcephaly.Applications:Unspecified applicationReactive species:Unspecified reactive speciesNichole Link et. al.PubMed 31735666
- Biology open 8:2019Distinct gene-selective roles for a network of core promoter factors in neural stem cell identity.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAlexandre Neves et. al.PubMed 30948355
- Cell 175:1931-1945.e182018Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesPriya S Shah,Nichole Link,Gwendolyn M Jang,Phillip P Sharp,Tongtong Zhu,Danielle L Swaney,Jeffrey R Johnson,John Von Dollen,Holly R Ramage,Laura Satkamp,Billy Newton,Ruth Hüttenhain,Marine J Petit,Tierney Baum,Amanda Everitt,Orly Laufman,Michel Tassetto,Michael Shales,Erica Stevenson,Gabriel N Iglesias,Leila Shokat,Shashank Tripathi,Vinod Balasubramaniam,Laurence G Webb,Sebastian Aguirre,A Jeremy Willsey,Adolfo Garcia-Sastre,Katherine S Pollard,Sara Cherry,Andrea V Gamarnik,Ivan Marazzi,Jack Taunton,Ana Fernandez-Sesma,Hugo J Bellen,Raul Andino,Nevan J KroganPubMed 30550790
- Cell reports 25:1561-1576.e72018The Scalloped and Nerfin-1 Transcription Factors Cooperate to Maintain Neuronal Cell Fate.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJoseph H A Vissers,Francesca Froldi,Jan Schröder,Anthony T Papenfuss,Louise Y Cheng,Kieran F HarveyPubMed 30404010
- Development (Cambridge, England) 145:2018Shep regulates neuronal remodeling by controlling transcription of its chromatin targets.Applications:Unspecified applicationReactive species:Unspecified reactive speciesDahong Chen et. al.PubMed 29158441
- Development (Cambridge, England) 144:3454-34642017Imp and Syp RNA-binding proteins govern decommissioning of neural stem cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesChing-Po Yang et. al.PubMed 28851709
Key facts
- Isotype
- IgG2b
- Host species
- Rat
- Storage buffer
pH: 7.5
Preservative: 0.02% Sodium azide
Constituents: 99% HEPES buffered saline- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
Reactivity data
Select an application| IHC | |
|---|---|
| Drosophila melanogaster | Tested |
IHC
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Drosophila melanogaster | Dilution info - | Notes - |
Associated Products
Select an associated product type
1 product for Alternative Product
Target data
Function
Transcriptional repressor of genes that require a bHLH protein for their transcription (PubMed:1427077, PubMed:24618901, PubMed:28899667). In the larval brain, required to maintain the self-renewal and identity of type II neuroblasts by regulating the expression of the transcriptional repressor erm together with other self-renewal transcriptional repressors such as klu and E(spl)mgamma-HLH (PubMed:21262215, PubMed:22357926, PubMed:23056424, PubMed:24618901, PubMed:28899667). As part of its role in neuroblasts development, has been shown to be a direct target of the Notch signaling pathway, however might work also independently of N/Notch (PubMed:21262215, PubMed:22357926, PubMed:23056424). In the developing larval and pupal brain, required for mushroom body differentiation (PubMed:22357926). Involved in sex determination and SXL transcription repression when in complex with the corepressor protein Groucho (PubMed:7651341, PubMed:8001118).
Alternative names
CG8704, dpn, Protein deadpan
Recommended products
Rat Monoclonal Deadpan antibody. Suitable for IHC and reacts with Drosophila melanogaster samples. Cited in 12 publications.
Key facts
- Isotype
- IgG2b
- Host species
- Rat
- Storage buffer
pH: 7.5
Preservative: 0.02% Sodium azide
Constituents: 99% HEPES buffered saline- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
- Clone number
- 11D1CH11
- Light chain type
- kappa
- Concentration
- Purification notes
>95% based on SDS-PAGE
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- +4°C
- Storage information
- Do Not Freeze
Notes
Want a custom formulation?
This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
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1 product image
![Immunohistochemistry - Anti-Deadpan antibody [11D1CH11] (ab195172), expandable thumbnail](https://content.abcam.com/products/images/deadpan-antibody-11d1ch11-ab195172--immunohistochemistry-img77435.jpg "Immunohistochemistry - Anti-Deadpan antibody [11D1CH11] (ab195172)")
Immunohistochemistry - Anti-Deadpan antibody [11D1CH11] (ab195172)
Immunohistochemistry analysis Drosophila stage 11 embryo labeling Deadpan with ab195172 at 10 μg/mL, followed by Alexa405 conjugated goat anti-rat secondary (at 10μg/mL).
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