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AB204429

Anti-DEPP antibody

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(1 Publication)

Rabbit Polyclonal DEPP antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human DEPP1 aa 1-150.

View Alternative Names

C10orf10, DEPP, FIG, DEPP1, Protein DEPP1, Decidual protein induced by progesterone, Fasting-induced gene protein

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DEPP antibody (AB204429)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DEPP antibody (AB204429)

Immunohistochemical analysis of formalin-fixed paraffin-embedded Human urinary bladder tissue labeling DEPP with ab204429 at 1/200.

Immunocytochemistry/ Immunofluorescence - Anti-DEPP antibody (AB204429)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-DEPP antibody (AB204429)

Immunofluorescent analysis of formalin fixed, Triton X-100 permealized U-2 OS cells labeling DEPP with ab204429 at 4 μg/ml (green).

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human DEPP1 aa 1-150. The exact immunogen used to generate this antibody is proprietary information.

Q9NTK1

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

DEPP also known as decidual protein induced by progesterone is a protein involved in various cellular processes. It has a molecular mass of around 23 kDa and is expressed in multiple tissues including the liver heart and skeletal muscles. DEPP is mainly located in the cytoplasm of the cells where it participates in cellular homeostasis by aiding in stress response mechanisms.
Biological function summary

DEPP plays a role in autophagy and apoptosis processes essential for maintaining cellular health by removing damaged organelles and cells. DEPP interacts with other proteins to form complexes that modulate these processes particularly in adaptive responses to environmental stressors like oxidative stress. Its expression changes in response to hormonal influences hinting at its value in reproductive biology and stress adaptation.

Pathways

DEPP integrates into the oxidative stress response and MAPK signaling pathways. These pathways are significant for controlling cell survival and death decisions in diverse environmental conditions. DEPP might interact with related proteins such as ASK1 and JNK playing a role in forwarding stress responses that maintain cellular equilibrium and contribute to organismal health.

DEPP shows potential involvement in neurodegenerative diseases and certain cancers. DEPP's stress response and autophagy roles suggest its influence on Alzheimer's disease pathology where protein aggregates and cellular stress are prevalent. In cancer DEPP can modulate tumor progression through its action on apoptosis-related proteins like Bcl-2 possibly impacting cancer cell survival and metastasis.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Acts as a critical modulator of FOXO3-induced autophagy via increased cellular ROS.
See full target information DEPP1
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Clinics (Sao Paulo, Brazil) 77:100019 PubMed35397366

2022

IRF4 suppresses osteogenic differentiation of BM-MSCs by transcriptionally activating miR-636/DOCK9 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Xuepu Zhang,Yue Zhang,Limin Yang,Yuexin Wu,Xiaohu Ma,Gang Tong,Zhaoliang Ban,Haosen Zhao
View all publications
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Product promise

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