JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB317384

Anti-DHRS1 antibody [S01-9E4]

Be the first to review this product! Submit a review

|

(0 Publication)

Rabbit Recombinant Monoclonal Dhrs1 antibody. Suitable for WB and reacts with Rat samples. Immunogen corresponding to Recombinant Fragment Protein within Human DHRS1.
1 Images
Western blot - Anti-DHRS1 Antibody [S01-9E4] (AB317384)
  • WB

Supplier Data

Western blot - Anti-DHRS1 Antibody [S01-9E4] (AB317384)

All lanes:

Western blot - Anti-DHRS1 Antibody [S01-9E4] (ab317384) at 1/1000 dilution

All lanes:

C6 cell lysate

Predicted band size: 34 kDa

false

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

S01-9E4

Isotype

IgG

Carrier free

No

Reacts with

Rat

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human DHRS1.

Q96LJ7

style
left-column

Complementary Products

Primary Antibodies

AB254671

Anti-RPS25 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RPS25 antibody (AB254671)

  • 0
  • 0
Primary Antibodies

AB254590

Anti-RASA2 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RASA2 antibody (AB254590)

  • 0
  • 0
Primary Antibodies

AB254700

Anti-UBE2Z antibody

Immunocytochemistry/ Immunofluorescence - Anti-UBE2Z antibody (AB254700)

  • 0
  • 0
Primary Antibodies

AB276055

Anti-SULT2B1 antibody [007] - BSA and Azide free

Recombinant

Immunoprecipitation - Anti-SULT2B1 antibody [007] - BSA and Azide free (AB276055)

  • 0
  • 0
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>" } } }
style
left-column

Product details

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification
Storage buffer
pH: 7.4 Preservative: 0.01% Sodium azide Constituents: 55.08% Water, 40% Glycerol (glycerin, glycerine), 0.98% Tris glycine, 0.88% Sodium chloride, 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

DHRS1 also known as dehydrogenase/reductase SDR family member 1 is an enzyme involved in biochemical reactions. It belongs to the short-chain dehydrogenase/reductase (SDR) family and has a mass of about 33 kDa. This enzyme participates in redox reactions specifically by catalyzing the oxidation and reduction processes involving small substrates. DHRS1 is mainly expressed in liver and kidney tissues which suggests its role in metabolic processes associated with these organs.
Biological function summary

DHRS1 plays an important role in lipid metabolism. It helps in the conversion of steroid precursors and participates in the inactivation of steroid hormones. This enzyme does not form part of a complex but interacts with other enzymes within the same family to maintain balanced metabolic functions. Its activity assists in ensuring proper physiological levels of various metabolites and hormones.

Pathways

DHRS1 integrates into the lipid metabolism and steroid hormone biosynthesis pathways. It interacts with key proteins involved in oxidative metabolism such as 11β-hydroxysteroid dehydrogenase contributing to the regulation and conversion processes within these pathways. These interactions are important in controlling the balance of metabolites and support the physiological functionality of lipids and hormones.

DHRS1 is associated with metabolic syndrome and non-alcoholic fatty liver disease (NAFLD). Changes in DHRS1 activity can affect lipid processing and hormone regulation leading to these metabolic conditions. It may connect to proteins like peroxisome proliferator-activated receptor gamma (PPARγ) which also influences lipid metabolism and has a role in the onset of metabolic diseases. Understanding DHRS1's interactions and alterations could provide insight into therapeutic targets for these conditions.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

See full target information Dhrs1
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com