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AB137528

Anti-Dishevelled 2 antibody

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(4 Publications)

Rabbit Polyclonal Dishevelled 2 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Recombinant Fragment Protein within Human DVL2 aa 200-550.

View Alternative Names

Segment polarity protein dishevelled homolog DVL-2, Dishevelled-2, DSH homolog 2, DVL2

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Dishevelled 2 antibody (AB137528)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Dishevelled 2 antibody (AB137528)

Immunohistochemical analysis of paraffin embedded Human lung squamous cell carcinoma tissue labelling Dishevelled 2 with ab137528 at 1/100 dilution.

Western blot - Anti-Dishevelled 2 antibody (AB137528)
  • WB

Unknown

Western blot - Anti-Dishevelled 2 antibody (AB137528)

7.5% SDS PAGE

All lanes:

Western blot - Anti-Dishevelled 2 antibody (ab137528) at 1/500 dilution

Lane 1:

Molt4 whole cell lysate at 30 µg

Lane 2:

Raji whole cell lysate at 30 µg

Predicted band size: 78 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human DVL2 aa 200-550. The exact immunogen used to generate this antibody is proprietary information.

O14641

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/1000", "IHCP-species-notes": "<p>Perform heat mediated antigen retrieval before commencing with IHC staining protocol using 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0).</p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Monkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Plays a role in the signal transduction pathways mediated by multiple Wnt genes (PubMed : 24616100). Participates both in canonical and non-canonical Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling.
See full target information DVL2

Publications (4)

Recent publications for all applications. Explore the full list and refine your search

Journal of biochemical and molecular toxicology 36:e23069 PubMed35411647

2022

Nicotine exposure of male mice protects offspring against carbon tetrachloride-induced acute liver injury.

Applications

Unspecified application

Species

Unspecified reactive species

Dong Zhang,Jingbo Dai,Yong Cao,Zhaoxia Wang,Zhiguang Qiao,Zhongdong Qiao

Toxicology letters 343:44-55 PubMed33640489

2021

Paternal nicotine exposure promotes hepatic fibrosis in offspring.

Applications

Unspecified application

Species

Unspecified reactive species

Dong Zhang,Jingbo Dai,Meixing Zhang,Yilin Xie,Yong Cao,Guang He,Wangjie Xu,Lianyun Wang,Zhiguang Qiao,Zhongdong Qiao

Journal of Cancer 10:4540-4551 PubMed31528218

2019

HOXC10 promotes migration and invasion via the WNT-EMT signaling pathway in oral squamous cell carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Bo-Wen Dai,Zhi-Min Yang,Ping Deng,Yan-Rong Chen,Zhi-Jing He,Xi Yang,Sheng Zhang,Han-Jiang Wu,Zhen-Hu Ren

Molecular carcinogenesis 57:640-652 PubMed29380446

2018

SH2B1 promotes epithelial-mesenchymal transition through the IRS1/β-catenin signaling axis in lung adenocarcinoma.

Applications

WB

Species

Human

Shaoqiang Wang,Yuanda Cheng,Yang Gao,Zhiwei He,Wolong Zhou,Ruimin Chang,Zhenzi Peng,Yingying Zheng,Chaojun Duan,Chunfang Zhang
View all publications

Product promise

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