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AB126054

Anti-Dlx1 antibody

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(5 Publications)

Rabbit Polyclonal DLX1 antibody. Suitable for WB and reacts with Human, Mouse, Rat samples. Cited in 5 publications. Immunogen corresponding to Recombinant Fragment Protein within Human DLX1 aa 1-250.

View Alternative Names

Homeobox protein DLX-1, DLX1

2 Images
Western blot - Anti-Dlx1 antibody (AB126054)
  • WB

Unknown

Western blot - Anti-Dlx1 antibody (AB126054)

12% SDS PAGE

All lanes:

Western blot - Anti-Dlx1 antibody (ab126054) at 1/3000 dilution

All lanes:

U87-MG whole cell lysate at 30 µg

Predicted band size: 27 kDa

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Western blot - Anti-Dlx1 antibody (AB126054)
  • WB

Supplier Data

Western blot - Anti-Dlx1 antibody (AB126054)

Samples were separated by 12% SDS-PAGE.

All lanes:

Western blot - Anti-Dlx1 antibody (ab126054) at 1/1000 dilution

Lane 1:

Mouse brain tissue extract at 50 µg

Lane 2:

Rat brain tissue extract at 50 µg

Secondary

All lanes:

HRP-conjugated anti-rabbit IgG antibody

Predicted band size: 27 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Rat, Human

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human DLX1 aa 1-250. The exact immunogen used to generate this antibody is proprietary information.

P56177

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" }, "Chicken": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 20% Glycerol (glycerin, glycerine), 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Plays a role as a transcriptional activator or repressor (PubMed : 14671321). Inhibits several cytokine signaling pathways, such as TGFB1, activin-A/INHBA and BMP4 by interfering with the transcriptional stimulatory activity of transcription factors, such as MSX2, FAST2, SMAD2 and SMAD3 during hematopoietic cell differentiation (PubMed : 14671321). Plays a role in terminal differentiation of interneurons, such as amacrine and bipolar cells in the developing retina (By similarity). Likely to play a regulatory role in the development of the ventral forebrain (By similarity). May play a role in craniofacial patterning and morphogenesis and may be involved in the early development of diencephalic subdivisions (By similarity).
See full target information DLX1
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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Experimental and therapeutic medicine 22:1163 PubMed34504608

2021

miR-184 delays cell proliferation, migration and invasion in prostate cancer by directly suppressing DLX1.

Applications

Unspecified application

Species

Unspecified reactive species

Gui-Geng Tan,Chang Xu,Wei-Kang Zhong,Chuan-Yun Wang

BMC urology 21:40 PubMed33740948

2021

MicroRNA-4429 suppresses proliferation of prostate cancer cells by targeting distal-less homeobox 1 and inactivating the Wnt/β-catenin pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Jinguo Wang,Sheng Xie,Jun Liu,Tao Li,Wanrong Wang,Ziping Xie

Journal of cellular and molecular medicine 23:5934-5948 PubMed31298493

2019

MicroRNA-539 functions as a tumour suppressor in prostate cancer via the TGF-β/Smad4 signalling pathway by down-regulating DLX1.

Applications

Unspecified application

Species

Unspecified reactive species

Baogang Sun,Yingying Fan,Aijun Yang,Lunan Liang,Jinghe Cao

Journal of cellular physiology 234:20206-20216 PubMed30980391

2019

Long noncoding RNA TUG1 regulates the development of oral squamous cell carcinoma through sponging miR-524-5p to mediate DLX1 expression as a competitive endogenous RNA.

Applications

Unspecified application

Species

Unspecified reactive species

Shuyan Liu,Li-Hong Liu,Wei-Wei Hu,Meng Wang

Nature communications 9:2929 PubMed30050033

2018

Epigenome-wide DNA methylation profiling in Progressive Supranuclear Palsy reveals major changes at DLX1.

Applications

WB

Species

Human

Axel Weber,Sigrid C Schwarz,Jörg Tost,Dietrich Trümbach,Pia Winter,Florence Busato,Pawel Tacik,Anita C Windhorst,Maud Fagny,Thomas Arzberger,Catriona McLean,John C van Swieten,Johannes Schwarz,Daniela Vogt Weisenhorn,Wolfgang Wurst,Till Adhikary,Dennis W Dickson,Günter U Höglinger,Ulrich Müller
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

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