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AB154714

Anti-DNAJC3 antibody

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(2 Publications)

Rabbit Polyclonal DNAJC3 antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human DNAJC3 aa 250-500.

View Alternative Names

P58IPK, PRKRI, DNAJC3, DnaJ homolog subfamily C member 3, Endoplasmic reticulum DNA J domain-containing protein 6, Protein kinase inhibitor of 58 kDa, ER-resident protein ERdj6, ERdj6, Protein kinase inhibitor p58

1 Images
Western blot - Anti-DNAJC3 antibody (AB154714)
  • WB

Unknown

Western blot - Anti-DNAJC3 antibody (AB154714)

7.5% SDS PAGE

All lanes:

Western blot - Anti-DNAJC3 antibody (ab154714) at 1/1000 dilution

Lane 1:

A431 whole cell lysate at 30 µg

Lane 2:

H1299 whole cell lysate at 30 µg

Lane 3:

HeLa whole cell lysate at 30 µg

Lane 4:

MOLT4 whole cell lysate at 30 µg

Lane 5:

Raji whole cell lysate at 30 µg

Predicted band size: 58 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human DNAJC3 aa 250-500. The exact immunogen used to generate this antibody is proprietary information.

Q13217

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Pig": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Involved in the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Acts as a negative regulator of the EIF2AK4/GCN2 kinase activity by preventing the phosphorylation of eIF-2-alpha at 'Ser-52' and hence attenuating general protein synthesis under ER stress, hypothermic and amino acid starving stress conditions (By similarity). Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity.
See full target information DNAJC3
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in pharmacology 15:1475102 PubMed39494346

2024

Proteomic study of medicinal mushroom extracts reveals antitumor mechanisms in an advanced colon cancer animal model via ribosomal biogenesis, translation, and metabolic pathways.

Applications

Unspecified application

Species

Unspecified reactive species

Boris Jakopovic,Anita Horvatić,Jurica Baranasic,Iris Car,Nada Oršolić,Ivan Jakopovich,Mirela Sedić,Sandra Kraljević Pavelić

Biomedicines 12: PubMed38540147

2024

Circulating Exosomes from Septic Mice Activate NF-κB/MIR17HG Pathway in Macrophages.

Applications

Unspecified application

Species

Unspecified reactive species

Shao-Chun Wu,Cheng-Shyuan Rau,Yi-Chan Wu,Chia-Jung Wu,Chia-Wen Tsai,Lien-Hung Huang,Chia-Wei Lin,Tsu-Hsiang Lu,Ming-Yu Yang,Ching-Hua Hsieh
View all publications
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