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AB205567

Anti-DNase I antibody [6D5]

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(1 Publication)

Mouse Monoclonal DNase I antibody. Carrier free. Suitable for WB and reacts with Recombinant fragment - Cow samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Cow DNASE1.

View Alternative Names

DNL1, DNASE1, Deoxyribonuclease-1, Deoxyribonuclease I, DNase I

1 Images
Western blot - Anti-DNase I antibody [6D5] (AB205567)
  • WB

Supplier Data

Western blot - Anti-DNase I antibody [6D5] (AB205567)

All lanes:

Western blot - Anti-DNase I antibody [6D5] (ab205567) at 0.2 µg/mL

All lanes:

Recombinant bovine DNaseI expressed into the supernatant of CHO cell culture medium. at 10 µL

Predicted band size: 31 kDa

false

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

6D5

Isotype

IgG1

Carrier free

Yes

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Cow DNASE1.

P00639

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Recombinant fragment - Cow": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.1-0.2 µg/mL", "WB-species-notes": "<p>WB: 0.1 to 0.2 μg/ml (bovine DNaseI) or 1 μg/ml (Human DNaseI)</p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Purification notes
ab205567 is purified from cell culture supernatant.
Storage buffer
pH: 7.4 Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs (PubMed : 2395459, PubMed : 3352748, PubMed : 4976790, PubMed : 5166750). Expressed by non-hematopoietic tissues and preferentially cleaves protein-free DNA (By similarity). Among other functions, seems to be involved in cell death by apoptosis (PubMed : 2395459). Binds specifically to G-actin and blocks actin polymerization (PubMed : 2395459). Together with DNASE1L3, plays a key role in degrading neutrophil extracellular traps (NETs) (By similarity). NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation (By similarity). Degradation of intravascular NETs by DNASE1 and DNASE1L3 is required to prevent formation of clots that obstruct blood vessels and cause organ damage following inflammation (By similarity).
See full target information DNASE1
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

International journal of pediatric otorhinolaryngo 110:100-104 PubMed29859567

2018

Tonsillar antimicrobial peptide (AMP) expression profiles of periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis (PFAPA) patients.

Applications

Unspecified application

Species

Unspecified reactive species

Umut Gazi,Martha Emmanuel Agada,Hanife Ozkayalar,Ceyhun Dalkan,Burcin Sanlidag,Mustafa Asım Safak,Gamze Mocan,Nerin Onder Bahceciler
View all publications
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Product promise

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