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AB168782

Anti-DNASE2 antibody

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(3 Publications)

Mouse Polyclonal DNASE2 antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human DNASE2.

View Alternative Names

DNASE2A, DNL2, DNASE2, Deoxyribonuclease-2-alpha, Acid DNase, Deoxyribonuclease II alpha, Lysosomal DNase II, R31240_2, DNase II alpha

2 Images
Immunocytochemistry/ Immunofluorescence - Anti-DNASE2 antibody (AB168782)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-DNASE2 antibody (AB168782)

Immunofluorescence analysis of paraformaldehyde-fixed HeLa cells, labeling DNASE2 using ab168782 at 10 μg/ml. Cells should be permeabilized by incubating for 15 minutes on ice with 2 mL of 0.1% Triton X-100 in PBS prior to staining.

Western blot - Anti-DNASE2 antibody (AB168782)
  • WB

Unknown

Western blot - Anti-DNASE2 antibody (AB168782)

All lanes:

Western blot - Anti-DNASE2 antibody (ab168782) at 1 µg/mL

Lane 1:

DNASE2 transfected 293T cell lysate at 15 µL

Lane 2:

Non transfected 293T cell lysate at 15 µL

Predicted band size: 40 kDa

false

Key facts

Host species

Mouse

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF, WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human DNASE2.

O00115

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "10 µg/mL", "ICCIF-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4 Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the clearance of nucleic acids generated through apoptosis, hence preventing autoinflammation (PubMed : 29259162, PubMed : 31775019). Necessary for proper fetal development and for definitive erythropoiesis in fetal liver and bone marrow, where it degrades nuclear DNA expelled from erythroid precursor cells (PubMed : 29259162).
See full target information DNASE2
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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

The journal of gene medicine 25:e3507 PubMed36999202

2023

Circ_0073228 serves as a competitive endogenous ribonucleic acid to facilitate proliferation and inhibit apoptosis of hepatocellular carcinoma cells by the miR-139-5p/deoxyribonuclease II axis.

Applications

Unspecified application

Species

Unspecified reactive species

Lu Bai,Zujiang Yu,Qinggang Li,Xiaobo Hu,Xiaorui Liu,Fulei Li,Shasha Li,Yanling Chen

Molecular metabolism 58:101451 PubMed35123128

2022

Crosstalk between TM4SF5 and GLUT8 regulates fructose metabolism in hepatic steatosis.

Applications

Unspecified application

Species

Unspecified reactive species

Hyejin Lee,Eunmi Kim,Eun-Ae Shin,Jong Cheol Shon,Hyunseung Sun,Ji Eon Kim,Jae Woo Jung,Haesong Lee,Yangie Pinanga,Dae-Geun Song,Kwang-Hyeon Liu,Jung Weon Lee

Journal of immunology (Baltimore, Md. : 1950) 203:2276-2290 PubMed31519860

2019

Intra- and Extracellular Degradation of Neutrophil Extracellular Traps by Macrophages and Dendritic Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Beatrice Lazzaretto,Bengt Fadeel
View all publications
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Product promise

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