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AB220878

Anti-Dock5 antibody

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(1 Publication)

Rabbit Polyclonal DOCK5 antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human DOCK5 aa 800-950.

View Alternative Names

Dedicator of cytokinesis protein 5, DOCK5

1 Images
Immunocytochemistry/ Immunofluorescence - Anti-Dock5 antibody (AB220878)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-Dock5 antibody (AB220878)

Immunofluorescent analysis of PFA-fixed, Triton X-100 permeabilized U-2 OS cells labeling Dock5 with ab220878 at 4 μg/ml (green).

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human DOCK5 aa 800-950. The exact immunogen used to generate this antibody is proprietary information.

Q9H7D0

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p>Fixation/Permeabilization: PFA/Triton X-100.</p>" }, "Mouse": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP (By similarity). Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed : 19004829).
See full target information DOCK5
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Nature 589:448-455 PubMed33328637

2020

Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis.

Applications

Unspecified application

Species

Unspecified reactive species

Ievgenia Pastushenko,Federico Mauri,Yura Song,Florian de Cock,Bob Meeusen,Benjamin Swedlund,Francis Impens,Delphi Van Haver,Matthieu Opitz,Manuel Thery,Yacine Bareche,Gaelle Lapouge,Marjorie Vermeersch,Yves-Rémi Van Eycke,Cédric Balsat,Christine Decaestecker,Youri Sokolow,Sergio Hassid,Alicia Perez-Bustillo,Beatriz Agreda-Moreno,Luis Rios-Buceta,Pedro Jaen,Pedro Redondo,Ramon Sieira-Gil,Jose F Millan-Cayetano,Onofre Sanmatrtin,Nicky D'Haene,Virginie Moers,Milena Rozzi,Jeremy Blondeau,Sophie Lemaire,Samuel Scozzaro,Veerle Janssens,Magdalena De Troya,Christine Dubois,David Pérez-Morga,Isabelle Salmon,Christos Sotiriou,Francoise Helmbacher,Cédric Blanpain
View all publications
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Product promise

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