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AB85367

Anti-Dopamine D2 Receptor antibody

3

(4 Reviews)

|

(36 Publications)

Rabbit Polyclonal Dopamine D2 Receptor antibody. Suitable for WB and reacts with Rat, Human, Mouse samples. Cited in 36 publications.

View Alternative Names

D(2) dopamine receptor, Dopamine D2 receptor, DRD2

2 Images
Western blot - Anti-Dopamine D2 Receptor antibody (AB85367)
  • WB

Supplier Data

Western blot - Anti-Dopamine D2 Receptor antibody (AB85367)

All lanes:

Western blot - Anti-Dopamine D2 Receptor antibody (ab85367) at 1 µg/mL

Lane 1:

Human Brian at 10 µg

Lane 2:

Rat Dopaminergic Nucleus at 10 µg

Lane 3:

Mouse Substantia Nigra at 10 µg

Secondary

All lanes:

Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/50000 dilution

Observed band size: 49 kDa

true

Exposure time: 12min

Western blot - Anti-Dopamine D2 Receptor antibody (AB85367)
  • WB

CiteAb

Western blot - Anti-Dopamine D2 Receptor antibody (AB85367)

Dopamine D2 Receptor western blot using anti-Dopamine D2 Receptor antibody ab85367. Publication image and figure legend from Kupnicka, P., Listos, J., et al., 2020, Int J Mol Sci, PubMed 32235357.

ab85367 was used in this publication in western blot. This may not be the same as the application(s) guaranteed by Abcam. For a full list of applications guaranteed by Abcam for ab85367 please see the product overview.

Representative Western blots and densitometric analysis of D1R (A) and D2R (B) protein expression levels (normalized to β-actin) in the brain of control (C), perinatally F-exposed (F), morphine administered (M), perinatally F-exposed, and morphine administered rats (F + M) in a morphine dependence experimental model in chosen brain structures. The results are expressed as means ± SD. * p < 0.05 (Mann–Whitney U test).

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Rat, Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>" }, "Chimpanzee": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Monkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (PubMed : 21645528). Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5 (By similarity).
See full target information DRD2

Publications (36)

Recent publications for all applications. Explore the full list and refine your search

NPJ Parkinson's disease 11:175 PubMed40537481

2025

Butyrate improves abnormal sleep architecture in a Parkinson's disease mouse model via BDNF/TrkB signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Wen-Xiang Duan,Wei-Ye Xie,Chen Ying,Wang Fen,Xiao-Yu Cheng,Cheng-Jie Mao,Jun-Yi Liu,Chun-Feng Liu

Cell death & disease 16:370 PubMed40346068

2025

Dopamine D receptor agonists abrogate neuroendocrine tumour angiogenesis to inhibit chemotherapy-refractory small cell lung cancer progression.

Applications

Unspecified application

Species

Unspecified reactive species

Sk Kayum Alam,Anuradha Pandit,Li Wang,Seyedeh Sahar Mortazavi Farsani,Britteny A Thiele,Parvathy Manoj,Marie Christine Aubry,Vivek Verma,Charles M Rudin,Ying-Chun Lo,Luke H Hoeppner

Scientific reports 15:15943 PubMed40335575

2025

Dopamine D2 receptor upregulation in dorsal striatum in the LRRK2-R1441C rat model of early Parkinson's disease revealed by in vivo PET imaging.

Applications

Unspecified application

Species

Unspecified reactive species

Teresa Delgado-Goñi,Natalie Connor-Robson,Milena Cioroch,Stephen Paisey,Christopher Marshall,Emma L Lane,David Hauton,James McCullagh,Peter J Magill,Stephanie J Cragg,Clare E Mackay,Richard Wade-Martins,Johannes C Klein

British journal of pharmacology 181:2794-2809 PubMed38644533

2024

Transient receptor potential ankyrin 1 channel modulates the abuse-related mechanisms of methamphetamine through interaction with dopamine transporter.

Applications

Unspecified application

Species

Unspecified reactive species

Kwang-Hyun Hur,Youyoung Lee,Audrey Lynn Donio,Seon-Kyung Kim,Bo-Ram Lee,Jee-Yeon Seo,Dooti Kundu,Kyeong-Man Kim,Stephen J Kohut,Seok-Yong Lee,Choon-Gon Jang

Current zoology 69:682-693 PubMed37876636

2023

Dopamine D2 receptors in the dorsomedial prefrontal cortex modulate social hierarchy in male mice.

Applications

Unspecified application

Species

Unspecified reactive species

Lai-Fu Li,Zi-Lin Li,Bai-Lin Song,Yi Jiang,Yan Wang,Hua-Wei Zou,Lun-Guang Yao,Ying-Juan Liu

Biology direct 18:43 PubMed37528429

2023

The antipsychotic medications aripiprazole, brexpiprazole and cariprazine are off-target respiratory chain complex I inhibitors.

Applications

Unspecified application

Species

Unspecified reactive species

Rachel E Hardy,Injae Chung,Yizhou Yu,Samantha H Y Loh,Nobuhiro Morone,Clement Soleilhavoup,Marco Travaglio,Riccardo Serreli,Lia Panman,Kelvin Cain,Judy Hirst,Luis M Martins,Marion MacFarlane,Kenneth R Pryde

Current research in toxicology 3:100093 PubMed36393872

2022

Developmental deltamethrin: Sex-specific hippocampal effects in Sprague Dawley rats.

Applications

Unspecified application

Species

Unspecified reactive species

Emily M Pitzer,Chiho Sugimoto,Samantha L Regan,Gary A Gudelsky,Michael T Williams,Charles V Vorhees

Evidence-based complementary and alternative medicine : eCAM 2022:9139841 PubMed36337583

2022

"Jing-Ning Granules" Can Alleviate Attention Deficit Hyperactivity Disorder in Rats by Modulating Dopaminergic D2/D1-Like Receptor-Mediated Signaling Pathways.

Applications

Unspecified application

Species

Unspecified reactive species

Jie Ding,Yiyun Ding,Jingjing Wu,Jialin Deng,Qingyang Yu,Junhong Wang

PloS one 17:e0274007 PubMed36112695

2022

Cognitive and behavioral effects of whole brain conventional or high dose rate (FLASH) proton irradiation in a neonatal Sprague Dawley rat model.

Applications

Unspecified application

Species

Unspecified reactive species

Michael T Williams,Chiho Sugimoto,Samantha L Regan,Emily M Pitzer,Adam L Fritz,Mathieu Sertorio,Anthony E Mascia,Ralph E Vatner,John P Perentesis,Charles V Vorhees

Nature metabolism 4:901-917 PubMed35879461

2022

Prolonged breastfeeding protects from obesity by hypothalamic action of hepatic FGF21.

Applications

Unspecified application

Species

Unspecified reactive species

Veronica Pena-Leon,Cintia Folgueira,Silvia Barja-Fernández,Raquel Pérez-Lois,Natália Da Silva Lima,Marion Martin,Violeta Heras,Sara Martinez-Martinez,Paola Valero,Cristina Iglesias,Mannon Duquenne,Omar Al-Massadi,Daniel Beiroa,Yara Souto,Miguel Fidalgo,Rasika Sowmyalakshmi,Diana Guallar,Juan Cunarro,Cecilia Castelao,Ana Senra,Patricia González-Saenz,Rocío Vázquez-Cobela,Rosaura Leis,Guadalupe Sabio,Helge Mueller-Fielitz,Markus Schwaninger,Miguel López,Sulay Tovar,Felipe F Casanueva,Emmanuel Valjent,Carlos Diéguez,Vincent Prevot,Rubén Nogueiras,Luisa M Seoane
View all publications

Product promise

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