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AB20066

Anti-Dopamine Receptor D1 antibody

4

(11 Reviews)

|

(49 Publications)

Rabbit Polyclonal Dopamine Receptor D1 antibody. Suitable for WB and reacts with Rat, Human samples. Cited in 49 publications. Immunogen corresponding to Synthetic Peptide within Human DRD1 aa 1-50.

View Alternative Names

D(1A) dopamine receptor, Dopamine D1 receptor, DRD1

1 Images
Western blot - Anti-Dopamine Receptor D1 antibody (AB20066)
  • WB

Unknown

Western blot - Anti-Dopamine Receptor D1 antibody (AB20066)

All lanes:

Western blot - Anti-Dopamine Receptor D1 antibody (ab20066) at 1 µg/mL

Lane 1:

Human brain tissue lysate - total protein (<a href='/en-us/products/unavailable/human-brain-tissue-lysate-total-protein-ab29466'>ab29466</a>) at 10 µg

Lane 2:

Rat Forebrain at 10 µg

Lane 3:

Rat Cortex Tissue Lysate at 10 µg

Secondary

All lanes:

Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

Predicted band size: 49 kDa

Observed band size: 45 kDa,48 kDa,70 kDa,75 kDa

true

Exposure time: 90s

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Rat, Human

Applications

WB

applications

Immunogen

Synthetic Peptide within Human DRD1 aa 1-50. The exact immunogen used to generate this antibody is proprietary information.

P21728

Specificity

Stains specific cells in various regions of PLP fixed Rat brain sections. This includes Medial septum, Nucleus accumbens, Dentate gyrus, Globus pallidus, Medial forebrain bundle, Cortex regions 1-3, Substantia Nigra reticulata, and the Ventral tegmental area. Cross reactivity: D1 Dopamine Receptor (9-21) 100%; D1 Dopamine Receptor 90%; D2 Dopamine Receptor (272-282) 0%; D2 Dopamine Receptor 0%; D3 Dopamine Receptor (2-10) 0%; D3 Dopamine Receptor 0; D4 Dopamine Receptor (176-185) 0%; D4 Dopamine Receptor 0%; D5 Dopamine Receptor (23-35) 0%; D5 Dopamine Receptor 0%

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purity
Whole antiserum
Storage buffer
Constituents: PBS, 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
See full target information DRD1
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Publications (49)

Recent publications for all applications. Explore the full list and refine your search

Fluids and barriers of the CNS 19:95 PubMed36437472

2022

Modulation of striatal glutamatergic, dopaminergic and cholinergic neurotransmission pathways concomitant with motor disturbance in rats with kaolin-induced hydrocephalus.

Applications

Unspecified application

Species

Unspecified reactive species

Li-Jin Chen,Jeng-Rung Chen,Guo-Fang Tseng

Frontiers in cellular neuroscience 16:893190 PubMed35711471

2022

Knockout of Dopamine D3 Receptor Gene Blocked Methamphetamine-Induced Distinct Changes of Dopaminergic and Glutamatergic Synapse in the Nucleus Accumbens Shell of Mice.

Applications

Unspecified application

Species

Unspecified reactive species

Shuai Wang,Ming Li,Linlan Su,Yu Wang,Dongliang Ma,Hongyan Wang,Jie Zhu,Teng Chen

Neuroscience 495:58-73 PubMed35643248

2022

Anterior Insular-nucleus Accumbens Pathway Controls Refeeding-induced Analgesia under Chronic Inflammatory Pain Condition.

Applications

Unspecified application

Species

Unspecified reactive species

Grace J Lee,Yea Jin Kim,Sang Wook Shim,Kihwan Lee,Seog Bae Oh

IBRO neuroscience reports 12:342-354 PubMed35572456

2022

Early life stress influences basal ganglia dopamine receptors and novel object recognition of adolescent and adult rats.

Applications

Unspecified application

Species

Unspecified reactive species

Ada Sinani,Andriana Vassi,Giota Tsotsokou,Maria Nikolakopoulou,Elias D Kouvelas,Ada Mitsacos

Molecular medicine (Cambridge, Mass.) 28:23 PubMed35189819

2022

Activation of dopamine receptor D1 promotes osteogenic differentiation and reduces glucocorticoid-induced bone loss by upregulating the ERK1/2 signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Jie Zhu,Chengcheng Feng,Weicheng Zhang,Zhidong Wang,Mengdan Zhong,Wenkai Tang,Zhifang Wang,Haiwei Shi,Zhengyu Yin,Jiandong Shi,Yu Huang,Long Xiao,Dechun Geng,Zhirong Wang

Frontiers in molecular neuroscience 14:779436 PubMed34955745

2021

Effects of Chemogenetic Inhibition of D1 or D2 Receptor-Containing Neurons of the Substantia Nigra and Striatum in Mice With Tourette Syndrome.

Applications

Unspecified application

Species

Unspecified reactive species

Lixue Lin,Yuye Lan,He Zhu,Lingling Yu,Shuang Wu,Wangyixuan Wan,Yang Shu,Hongchun Xiang,Tengfei Hou,Hong Zhang,Yan Ma,Wen Su,Man Li

Journal of molecular neuroscience : MN 71:2583-2592 PubMed34125397

2021

Liposomal Form of L-Dopa and SH-Sy5y Cell-Derived Exosomes Modulate the Tyrosine Hydroxylase/Dopamine Receptor D2 Signaling Pathway in Parkinson's Rat Models.

Applications

Unspecified application

Species

Unspecified reactive species

Parastoo Zarrin,Mahmood Dehghani Ashkezari,Seyed Morteza Seifati

Biomedicines 9: PubMed33923250

2021

Dopamine Transporter Genetic Reduction Induces Morpho-Functional Changes in the Enteric Nervous System.

Applications

Unspecified application

Species

Unspecified reactive species

Silvia Cerantola,Valentina Caputi,Gabriella Contarini,Maddalena Mereu,Antonella Bertazzo,Annalisa Bosi,Davide Banfi,Dante Mantini,Cristina Giaroni,Maria Cecilia Giron

Frontiers in psychiatry 12:645081 PubMed33776821

2021

Expression of Dopamine D and Serotonin 5-HT Receptors in Blood Mononuclear Cells in Schizophrenia.

Applications

Unspecified application

Species

Unspecified reactive species

Adam Wysokiński,Elżbieta Kozłowska,Ewa Szczepocka,Anna Łucka,Justyna Agier,Ewa Brzezińska-Błaszczyk,Katarzyna Sobierajska

Science advances 6: PubMed33208359

2020

Trappc9 deficiency in mice impairs learning and memory by causing imbalance of dopamine D1 and D2 neurons.

Applications

Unspecified application

Species

Unspecified reactive species

Yuting Ke,Meiqian Weng,Gaurav Chhetri,Muhammad Usman,Yan Li,Qing Yu,Yingzhuo Ding,Zejian Wang,Xiaolong Wang,Pinky Sultana,Marian DiFiglia,Xueyi Li
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions
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