JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB23701

Anti-DPL antibody

1

(2 Reviews)

|

(0 Publication)

Rabbit Polyclonal DPL antibody. Suitable for WB and reacts with Mouse samples. Immunogen corresponding to Synthetic Peptide within Human PRND aa 100-150.

View Alternative Names

DPL, UNQ1830/PRO3443, PRND, Prion-like protein doppel, PrPLP, Prion protein 2

1 Images
Western blot - Anti-DPL antibody (AB23701)
  • WB

Unknown

Western blot - Anti-DPL antibody (AB23701)

All lanes:

Western blot - Anti-DPL antibody (ab23701) at 2 µg/mL

Lane 1:

27ug mouse spleen 100k x g supernatant.

Lane 2:

54ug mouse spleen 100k x g supernatant.

Predicted band size: 20 kDa

Observed band size: 19 kDa,25 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse

Applications

WB

applications

Immunogen

Synthetic Peptide within Human PRND aa 100-150. The exact immunogen used to generate this antibody is proprietary information.

Q9UKY0

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "2 µg/mL", "WB-species-notes": "<p></p>" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: Tris buffered saline, 50% Glycerol (glycerin, glycerine), 0.1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The term DPL often refers to a protein involved in cellular processes and may also be known as "dpl" or "aa dpl". Its exact molecular mass can vary based on the isoform and the species in which it is found. DPL is expressed in various tissues including the brain liver and heart making it an important target for therapeutic studies in diverse physiological contexts. Researchers investigate this protein to understand better its mechanical roles in maintaining cellular functions.
Biological function summary

DPL participates in cellular signaling and structural integrity. It sometimes acts as part of a larger protein complex facilitating communication and interactions between cells. The molecular interactions with other proteins help maintain cellular homeostasis. The coupling with other cellular components might also contribute to energy metabolism and cytoskeletal organization critical to cell health and function.

Pathways

DPL plays a role in specific signaling pathways like the MAPK/ERK and PI3K/AKT pathways. These pathways are significant for cell proliferation differentiation and survival. DPL interacts with other proteins such as Raf and PI3K enabling these signaling cascades essential for cellular responses to external stimuli. The pathways involving DPL are important for understanding various cellular mechanisms and how they relate to broader biological activities across systems.

DPL has connections to certain conditions including cancer and cardiovascular diseases. Abnormal expression or mutations in DPL can disrupt normal cellular signaling contributing to tumorigenesis and heart dysfunction. In cancer DPL may interact with oncogenes like KRAS affecting tumor growth and spread. In heart disorders alterations in DPL-associated pathways could impact cardiac cell function connecting it to other proteins such as troponin related to heart muscle contraction abnormalities.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Required for normal acrosome reaction and for normal male fertility (By similarity). Can bind Cu(2+) (PubMed : 15218028, PubMed : 20411530).
See full target information PRND
style
left-column
style
left-column
style
right-column

Complementary Products

Primary Antibodies

AB134045

Anti-CD63 antibody [EPR5702] - Late Endosome Marker

RabMAb|Recombinant|KO Validated|Lab Essentials|Trial Size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD63 antibody [EPR5702] - Late Endosome Marker (AB134045)

  • 3
  • 6
Primary Antibodies

AB14748

Anti-ATP5A antibody [15H4C4] - Mitochondrial Marker

BOND RX™ Validated|Lab Essentials

Western blot - Anti-ATP5A antibody [15H4C4] - Mitochondrial Marker (AB14748)

  • 5
  • 27
Primary Antibodies

AB203829

Anti-ZEB1 antibody [EPR17375]

RabMAb|Recombinant|KO Validated

Western blot - Anti-ZEB1 antibody [EPR17375] (AB203829)

  • 3
  • 3
Primary Antibodies

AB180144

Anti-CRM1 antibody [EPR14123(B)]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-CRM1 antibody [EPR14123(B)] (AB180144)

  • 0
  • 0

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com