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AB150565

Anti-DUSP22 antibody

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(1 Publication)

Rabbit Polyclonal DUSP22 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human DUSP22.

View Alternative Names

JSP1, LMWDSP2, MKPX, DUSP22, Dual specificity protein phosphatase 22, JNK pathway associated phosphatase, JNK-stimulatory phosphatase-1, Low molecular weight dual specificity phosphatase 2, Mitogen-activated protein kinase phosphatase x, JKAP, JSP-1, LMW-DSP2, MAP kinase phosphatase x, MKP-x

1 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DUSP22 antibody (AB150565)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DUSP22 antibody (AB150565)

Immunohistochemical analysis of paraffin embedded Human kidney tissue labelling DUSP22 with ab150565 at 22 ug/ml

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Synthetic Peptide within Human DUSP22. The exact immunogen used to generate this antibody is proprietary information.

Q9NRW4

Specificity

BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DUSP15 (59%).

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "2-22 µg/mL", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval before commencing with IHC staining protocol." }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Common marmoset": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Cow": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Gorilla": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Horse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Monkey": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rabbit": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Dual specificity phosphatase; can dephosphorylate both phosphotyrosine and phosphoserine or phosphothreonine residues (PubMed : 24714587, PubMed : 38225265). Activates the JNK signaling pathway (PubMed : 11717427). Inhibits T-cell receptor signaling and T-cell mediated immune responses, acting, at least in part, by inducing degradation of E3 ubiquitin ligase UBR2 (PubMed : 24714587, PubMed : 38225265). Dephosphorylates and thereby induces 'Lys-48'-linked ubiquitination of UBR2, leading to proteasomal degradation of UBR2 (PubMed : 38225265). Dephosphorylates and thereby inactivates tyrosine kinase LCK (PubMed : 24714587). Inhibits UBR2-mediated 'Lys-63'-linked ubiquitination of LCK (PubMed : 38225265). May play a role in B-cell receptor (BCR) signaling and B-cell function (By similarity).
See full target information DUSP22
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Stroke 51:2197-2207 PubMed32486965

2020

Mesenchymal Behavior of the Endothelium Promoted by SMAD6 Downregulation Is Associated With Brain Arteriovenous Malformation Microhemorrhage.

Applications

Unspecified application

Species

Unspecified reactive species

Weilun Fu,Ran Huo,Zihan Yan,Hongyuan Xu,Hao Li,Yuming Jiao,Linjian Wang,Jiancong Weng,Jie Wang,Shuo Wang,Yong Cao,Jizong Zhao
View all publications
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Product promise

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