AB117509

DyLight® 488 Anti-S tag antibody

Name: DyLight® 488 Anti-S tag antibody (ab117509) | Abcam
Brand: Abcam Limited
SKU: AB117509
Price: 515 USD
Availability: InStock

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(2 Publications)

Rabbit Polyclonal S tag antibody - conjugated to DyLight® 488. Suitable for Flow Cyt, ICC/IF and reacts with Tag samples. Cited in 2 publications.

View Alternative Names

KETAAAKFERQHMDS tag antibody, S peptide, S peptide epitope tag

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Conjugation

DyLight® 488

Excitation/Emission

Ex: 493nm, Em: 518nm

Carrier free

Applications

ICC/IF, Flow Cyt

applications

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Tag": { "FlowCyt-species-checked": "guaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 8.2 Constituents: 99% Tris buffered saline

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The S tag is a peptide sequence derived from ribonuclease A commonly used in molecular biology for protein purification and detection. This tag has a molecular mass of approximately 2 kDa. Researchers often utilize S tags for their small size which minimizes interference with protein function. The S tag is typically expressed as a fusion with the protein of interest which enables it to be used as a versatile tool in a variety of expression systems.

Biological function summary

S tags do not independently participate in cellular functions but instead facilitate experimental procedures. When fused to a protein the S tag allows for simple detection and purification using anti-S tag antibodies. This functionality makes it possible to isolate and study the protein of interest without affecting its native activity significantly. While S tags do not form part of any specific complex they interact with complexes like alkaline phosphatase in experimental applications to enhance detection signals.

Pathways

S tags themselves do not have inherent roles in cellular pathways. However they are used as a tool in studies involving signal transduction or metabolic pathways where their presence aids in tracking or manipulating pathway components. Due to their utility S tags can be connected indirectly to proteins such as ALP (alkaline phosphatase) by enabling pathway mapping in experiments.

S tags do not directly relate to specific conditions but are instrumental in research. For instance they allow scientists to study proteins connected to cancer or metabolic disorders more effectively. In research related to metabolic disorders S-tagged proteins can be linked to alkaline phosphatase helping in investigations to understand the role of alkaline phosphatase in calcium metabolism issues.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

See full target information S tag

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 12:3970 PubMed34172739

2021

The nanoscale molecular morphology of docked exocytic dense-core vesicles in neuroendocrine cells.

Applications

Unspecified application

Species

Unspecified reactive species

Bijeta Prasai,Gideon J Haber,Marie-Paule Strub,Regina Ahn,John A Ciemniecki,Kem A Sochacki,Justin W Taraska

Nature communications 12:2046 PubMed33824347

2021

Deficiency of TMEM53 causes a previously unknown sclerosing bone disorder by dysregulation of BMP-SMAD signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Long Guo,Aritoshi Iida,Gandham SriLakshmi Bhavani,Kalpana Gowrishankar,Zheng Wang,Jing-Yi Xue,Juan Wang,Noriko Miyake,Naomichi Matsumoto,Takanori Hasegawa,Yusuke Iizuka,Masashi Matsuda,Tomoki Nakashima,Masaki Takechi,Sachiko Iseki,Shinsei Yambe,Gen Nishimura,Haruhiko Koseki,Chisa Shukunami,Katta M Girisha,Shiro Ikegawa

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

DyLight® 488 Anti-S tag antibody

Key facts

Host species

Clonality

Isotype

Conjugation

Excitation/Emission

Carrier free

Applications

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Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (2)

Product promise