Mouse Monoclonal C-Myc/MYC antibody - conjugated to DyLight® 550. Carrier free. Suitable for Flow Cyt, ICC/IF and reacts with Tag samples. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human MYC.
pH: 8.2
Constituents: 99% Tris buffered saline
| Flow Cyt | ICC/IF | |
|---|---|---|
| Tag | Expected | Expected |
| Species | Dilution info | Notes |
|---|---|---|
Species Tag | Dilution info Use at an assay dependent concentration. | Notes - |
| Species | Dilution info | Notes |
|---|---|---|
Species Tag | Dilution info 1/500.00000 - 1/5000.00000 | Notes - |
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Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3' (PubMed:24940000, PubMed:25956029). Activates the transcription of growth-related genes (PubMed:24940000, PubMed:25956029). Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed:24940000, PubMed:25956029). Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells (By similarity). Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform (PubMed:20010808).
BHLHE39, MYC, Myc proto-oncogene protein, Class E basic helix-loop-helix protein 39, Proto-oncogene c-Myc, Transcription factor p64, bHLHe39
Mouse Monoclonal C-Myc/MYC antibody - conjugated to DyLight® 550. Carrier free. Suitable for Flow Cyt, ICC/IF and reacts with Tag samples. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human MYC.
pH: 8.2
Constituents: 99% Tris buffered saline
This antibody is specific for Myc tagged proteins. The Myc tag epitope (EQKLISEEDL) is located at the dimerization site of c-myc and therefore this antibody does not perform well at recognizing endogenous c-myc.
We have tested this species and application combination and it works. It is covered by our product promise.
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
We do not recommend this combination. It is not covered by our product promise.
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